Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   SPYJRS4_RS00690 Genome accession   NZ_AP012335
Coordinates   107814..108767 (+) Length   317 a.a.
NCBI ID   WP_021340467.1    Uniprot ID   -
Organism   Streptococcus pyogenes JRS4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 102814..113767
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYJRS4_RS00650 (SPYJRS4_0092) - 103641..104006 (+) 366 WP_002986560.1 DUF1033 family protein -
  SPYJRS4_RS00655 (SPYJRS4_0093) comGA 104099..105037 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  SPYJRS4_RS00660 (SPYJRS4_0094) comGB 104973..106007 (+) 1035 WP_011184088.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPYJRS4_RS00665 (SPYJRS4_0095) comGC 106009..106335 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  SPYJRS4_RS00670 (SPYJRS4_0096) comGD 106310..106738 (+) 429 WP_011184089.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPYJRS4_RS00675 (SPYJRS4_0097) comGE 106695..106979 (+) 285 WP_027968839.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPYJRS4_RS00680 (SPYJRS4_0098) comGF 106972..107406 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPYJRS4_RS00685 (SPYJRS4_0099) comGG 107390..107716 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  SPYJRS4_RS00690 (SPYJRS4_0100) comGH 107814..108767 (+) 954 WP_021340467.1 class I SAM-dependent methyltransferase Machinery gene
  SPYJRS4_RS00695 (SPYJRS4_0101) - 108826..110022 (+) 1197 WP_002986533.1 acetate kinase -
  SPYJRS4_RS00700 (SPYJRS4_0102) - 110209..110517 (+) 309 WP_011017251.1 hypothetical protein -
  SPYJRS4_RS00705 (SPYJRS4_0103) proC 110600..111370 (-) 771 WP_011184092.1 pyrroline-5-carboxylate reductase -
  SPYJRS4_RS00710 (SPYJRS4_0104) pepA 111418..112485 (-) 1068 WP_011184093.1 glutamyl aminopeptidase -
  SPYJRS4_RS00715 (SPYJRS4_0106) - 112950..113234 (+) 285 WP_011888537.1 DUF4651 domain-containing protein -
  SPYJRS4_RS00720 (SPYJRS4_0107) - 113231..113548 (+) 318 WP_002986515.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35971.05 Da        Isoelectric Point: 4.7205

>NTDB_id=54815 SPYJRS4_RS00690 WP_021340467.1 107814..108767(+) (comGH) [Streptococcus pyogenes JRS4]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFVQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=54815 SPYJRS4_RS00690 WP_021340467.1 107814..108767(+) (comGH) [Streptococcus pyogenes JRS4]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAATTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCCCATTTTGTTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(68-288)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

66.456

99.685

0.662
  comGH Streptococcus mutans UA140

66.139

99.685

0.659