Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LRM32_RS09680 Genome accession   NZ_CP088131
Coordinates   1998041..1998697 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 81     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1993041..2003697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LRM32_RS09645 (LRM32_09645) dcyD 1993608..1994594 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  LRM32_RS09650 (LRM32_09650) tcyL 1994609..1995277 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LRM32_RS09655 (LRM32_09655) tcyN 1995274..1996026 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LRM32_RS09660 (LRM32_09660) - 1996256..1996549 (+) 294 Protein_1892 autoinducer binding domain-containing protein -
  LRM32_RS24485 - 1996634..1997589 (-) 956 Protein_1893 IS5 family transposase -
  LRM32_RS09675 (LRM32_09675) - 1997650..1997745 (-) 96 Protein_1894 hypothetical protein -
  LRM32_RS24490 - 1997783..1997899 (-) 117 WP_001302039.1 hypothetical protein -
  LRM32_RS09680 (LRM32_09680) letA 1998041..1998697 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LRM32_RS09685 (LRM32_09685) uvrC 1998694..2000526 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  LRM32_RS09690 (LRM32_09690) pgsA 2000583..2001129 (+) 547 Protein_1898 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LRM32_RS09710 (LRM32_09710) - 2001823..2002563 (-) 741 WP_060617843.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=547295 LRM32_RS09680 WP_000611328.1 1998041..1998697(+) (letA) [Escherichia coli strain 81]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=547295 LRM32_RS09680 WP_000611328.1 1998041..1998697(+) (letA) [Escherichia coli strain 81]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482