Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   J3R86_RS08550 Genome accession   NZ_CP071589
Coordinates   1861237..1861866 (-) Length   209 a.a.
NCBI ID   WP_002464447.1    Uniprot ID   G5JJU2
Organism   Staphylococcus simiae strain 17941E     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1856237..1866866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J3R86_RS08520 (J3R86_08520) - 1856487..1857017 (-) 531 WP_207516931.1 acyl-CoA thioesterase -
  J3R86_RS08525 (J3R86_08525) - 1857087..1858331 (-) 1245 WP_207516932.1 aminopeptidase -
  J3R86_RS08530 (J3R86_08530) - 1858345..1858545 (-) 201 WP_088177495.1 DUF1128 family protein -
  J3R86_RS08535 (J3R86_08535) - 1858692..1859156 (+) 465 WP_207516933.1 low molecular weight protein-tyrosine-phosphatase -
  J3R86_RS08540 (J3R86_08540) - 1859163..1859438 (+) 276 WP_207516934.1 YtxH domain-containing protein -
  J3R86_RS08545 (J3R86_08545) - 1859809..1861026 (+) 1218 WP_207516935.1 YihY/virulence factor BrkB family protein -
  J3R86_RS08550 (J3R86_08550) vraR 1861237..1861866 (-) 630 WP_002464447.1 two-component system response regulator VraR Regulator
  J3R86_RS08555 (J3R86_08555) vraS 1861856..1862899 (-) 1044 WP_207516936.1 sensor histidine kinase Regulator
  J3R86_RS08560 (J3R86_08560) liaF 1862896..1863597 (-) 702 WP_207516937.1 cell wall-active antibiotics response protein LiaF -
  J3R86_RS08565 (J3R86_08565) - 1863612..1863998 (-) 387 WP_207516938.1 hypothetical protein -
  J3R86_RS08570 (J3R86_08570) map 1864235..1864990 (-) 756 WP_207516939.1 type I methionyl aminopeptidase -
  J3R86_RS08575 (J3R86_08575) - 1865167..1866153 (+) 987 WP_207516940.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23620.19 Da        Isoelectric Point: 4.8783

>NTDB_id=546740 J3R86_RS08550 WP_002464447.1 1861237..1861866(-) (vraR) [Staphylococcus simiae strain 17941E]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGESGKDAISKAHDLNPDLILMDLLMEDMDGVEATTQIKKDLPHIKVL
MLTSFIEDNEVYRALDAGVDSYILKTTSAKDIADAVRKTYNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=546740 J3R86_RS08550 WP_002464447.1 1861237..1861866(-) (vraR) [Staphylococcus simiae strain 17941E]
ATGACGATTAAAGTATTATTTGTGGATGACCATGAAATGGTTCGTATCGGTATTTCTAGTTATTTATCAACACAAAGTGA
TATAGAAGTAGTAGGTGAAGGTGAATCAGGTAAGGATGCTATATCGAAGGCACATGACTTGAATCCGGACTTAATTTTAA
TGGATTTATTAATGGAAGATATGGATGGTGTCGAAGCTACTACTCAAATAAAAAAAGACTTACCACATATTAAAGTATTA
ATGCTAACAAGCTTTATAGAAGATAATGAAGTTTATCGTGCTTTGGATGCTGGCGTTGATAGTTATATTTTAAAAACAAC
AAGTGCTAAAGATATTGCTGATGCTGTACGTAAAACATATAATGGGGAATCTGTTTTTGAACCTGAAGTATTAGTAAAAA
TGCGTAATCGTATGAAAAAACGAGCTGAATTATATGAAATGTTAACAGAACGAGAAATGGAAATATTGTTACTTATTGCT
AAAGGCTATTCCAATCAGGAAATCGCTAGTGCATCACATATCACCATAAAAACAGTTAAAACTCATGTAAGTAACATATT
AAGTAAATTGGAAGTACAAGATAGAACACAAGCTGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JJU2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.694

100

0.957
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373