Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   HIV01_RS09765 Genome accession   NZ_CP071517
Coordinates   2088533..2089981 (+) Length   482 a.a.
NCBI ID   WP_200606751.1    Uniprot ID   -
Organism   Lysobacter arenosi strain R7     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2090962..2104331 2088533..2089981 flank 981


Gene organization within MGE regions


Location: 2088533..2104331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIV01_RS09765 (HIV01_009765) pilR 2088533..2089981 (+) 1449 WP_200606751.1 sigma-54 dependent transcriptional regulator Regulator
  HIV01_RS09770 (HIV01_009770) pilA 2090381..2090803 (+) 423 WP_200606752.1 pilin Machinery gene
  HIV01_RS09775 (HIV01_009775) - 2090962..2091363 (+) 402 WP_200606753.1 pilin -
  HIV01_RS09780 (HIV01_009780) - 2091439..2093343 (+) 1905 WP_200606754.1 hypothetical protein -
  HIV01_RS09785 (HIV01_009785) - 2093370..2094218 (+) 849 WP_200606755.1 hypothetical protein -
  HIV01_RS09790 (HIV01_009790) - 2094220..2095518 (+) 1299 WP_207526915.1 oligosaccharide flippase family protein -
  HIV01_RS09795 (HIV01_009795) - 2095555..2096619 (-) 1065 WP_200606757.1 glycosyltransferase family 4 protein -
  HIV01_RS09800 (HIV01_009800) - 2096623..2097711 (-) 1089 WP_200606758.1 UDP-N-acetylglucosamine 2-epimerase -
  HIV01_RS09805 (HIV01_009805) - 2097708..2098580 (-) 873 WP_200606760.1 glycosyltransferase family 2 protein -
  HIV01_RS09810 (HIV01_009810) pilB 2098753..2100477 (+) 1725 WP_200606762.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HIV01_RS09815 (HIV01_009815) pilC 2100619..2101875 (+) 1257 WP_200606764.1 type II secretion system F family protein Machinery gene
  HIV01_RS09820 (HIV01_009820) pilD 2101913..2102776 (+) 864 WP_200606766.1 A24 family peptidase Machinery gene
  HIV01_RS09825 (HIV01_009825) - 2102805..2103554 (-) 750 WP_200606767.1 class I SAM-dependent methyltransferase -
  HIV01_RS09830 (HIV01_009830) coaE 2103708..2104331 (+) 624 WP_200606768.1 dephospho-CoA kinase -

Sequence

Protein


Download         Length: 482 a.a.        Molecular weight: 52092.77 Da        Isoelectric Point: 6.2784

>NTDB_id=545894 HIV01_RS09765 WP_200606751.1 2088533..2089981(+) (pilR) [Lysobacter arenosi strain R7]
MAETRSALVVDDERDIRELLVMTLGRMGLRCDTASTIGEARSQLSRNRYDLCLTDMRLPDGSGMDLVAEISQKHPETPVA
MITAFGNVEAAVEALKAGAFDFVAKPVDLAVLRDLVRHALDLNESRRSAPPADAVAARLYGQSPAMTTLRQTIAKVARSQ
APVYIVGESGVGKELVARTIHAEGGRASGPFVPVNCGAIPAELMESEFFGHKKGSFTGAHADKPGLFQSADGGTLFLDEI
AELPLAMQVKLLRAIQEKSIRPVGANSEVPVDVRILSATHKDLASLVADGRFRQDLYYRINVIELRVPPLRERQDDLPGL
VLMVLKRLATAQSRPVPALSDDALGVLRSYAFPGNVRELENILERALALAEDEILTAEDLRLPQVAQAQSAVFPNTGNAT
TAASPAPAPIAVAGQPMMAIDPRTLNPRDTASSPLPSYIEEIERAAIQQALQENRYNKTRTAAALGITFRALRYKLKKLG
ID

Nucleotide


Download         Length: 1449 bp        

>NTDB_id=545894 HIV01_RS09765 WP_200606751.1 2088533..2089981(+) (pilR) [Lysobacter arenosi strain R7]
ATGGCCGAAACACGTAGTGCACTGGTGGTCGACGACGAACGCGACATTCGCGAGTTGCTCGTCATGACATTGGGGAGGAT
GGGATTGCGTTGCGACACCGCCTCCACCATCGGGGAGGCACGCAGCCAGCTGTCCCGGAATCGCTACGACCTGTGCCTGA
CCGACATGCGCCTGCCTGACGGCTCGGGCATGGACCTGGTCGCCGAGATCAGCCAGAAGCACCCCGAGACCCCGGTCGCC
ATGATCACCGCCTTCGGCAATGTCGAAGCCGCGGTCGAGGCATTGAAGGCCGGTGCGTTCGACTTCGTCGCCAAACCCGT
CGACCTGGCCGTGTTGCGCGACCTGGTCCGCCACGCCCTGGACCTCAACGAAAGCCGCCGCAGCGCGCCGCCGGCCGACG
CCGTCGCCGCCCGCCTGTACGGCCAGTCGCCAGCCATGACCACGCTGCGCCAGACGATTGCCAAGGTCGCGCGCAGCCAG
GCGCCGGTCTACATCGTCGGCGAGTCGGGCGTGGGCAAGGAGCTGGTCGCCCGCACCATTCACGCCGAAGGCGGCCGCGC
CAGCGGACCGTTCGTCCCGGTCAACTGCGGCGCGATCCCGGCCGAGCTGATGGAGAGCGAGTTCTTCGGCCACAAGAAGG
GCAGCTTCACCGGCGCCCATGCCGACAAGCCCGGCCTGTTCCAGAGCGCCGATGGCGGCACCCTGTTCCTCGACGAAATC
GCCGAGCTGCCGCTGGCGATGCAGGTCAAGCTGCTGCGTGCCATCCAGGAAAAGTCGATCCGCCCGGTCGGTGCCAACAG
CGAAGTGCCGGTGGATGTACGCATCCTCTCGGCCACGCACAAGGACCTGGCCTCGCTGGTCGCCGATGGTCGCTTCCGCC
AGGATCTTTACTACCGCATCAATGTGATCGAGCTGCGCGTGCCGCCGCTTCGTGAGCGCCAGGATGACCTGCCCGGCCTG
GTGCTGATGGTGCTCAAGCGCCTCGCCACGGCGCAGTCGCGCCCGGTGCCCGCGCTGAGCGACGACGCCCTCGGGGTCCT
GCGCAGTTATGCGTTCCCGGGCAACGTGCGCGAACTGGAGAACATCCTCGAGCGTGCGCTTGCGCTTGCCGAAGACGAGA
TCCTGACGGCCGAAGACCTGCGCCTGCCACAGGTCGCCCAAGCCCAGAGCGCGGTGTTCCCGAACACGGGCAACGCCACG
ACCGCCGCATCGCCAGCGCCCGCCCCGATCGCGGTGGCCGGCCAGCCGATGATGGCGATCGACCCGCGCACGCTCAATCC
GCGCGATACCGCCAGCAGCCCGCTCCCCTCTTATATAGAGGAGATCGAGCGCGCGGCGATCCAGCAGGCGCTGCAGGAAA
ACCGCTACAACAAGACCCGTACTGCGGCCGCGCTCGGCATTACCTTCCGCGCGCTGCGGTACAAGCTGAAGAAACTCGGG
ATCGATTGA

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(439-479)

Response regulator receiver domain (Response_reg)

(8-116)

Sigma-54 interaction domain (Sigma54_activat)

(140-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

58.628

99.793

0.585
  pilR Acinetobacter baumannii strain A118

47.412

100

0.475