Detailed information NTG0544726

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: J0J33_RS04635
• Genome accession: NZ_CP071295
• Coordinates: 931598..933088 (+)
• Length: 496 a.a.
• NCBI ID: WP_019293246.1
• Uniprot ID: A0AAJ2ML94
• Organism: Lactococcus sp. LG1267
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 926598..938088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0J33_RS04610 (J0J33_04610)	pfkB	926746..927672 (+)	927	WP_165719430.1	1-phosphofructokinase	-
J0J33_RS04615 (J0J33_04615)	-	927687..929591 (+)	1905	WP_019293248.1	fructose-specific PTS transporter subunit EIIC	-
J0J33_RS04620 (J0J33_04620)	-	929703..929945 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
J0J33_RS04625 (J0J33_04625)	-	930162..930713 (+)	552	WP_206888295.1	DUF177 domain-containing protein	-
J0J33_RS04630 (J0J33_04630)	covR	930815..931510 (+)	696	WP_206921810.1	response regulator transcription factor	Regulator
J0J33_RS04635 (J0J33_04635)	covS	931598..933088 (+)	1491	WP_019293246.1	HAMP domain-containing histidine kinase	Regulator
J0J33_RS04640 (J0J33_04640)	-	933484..935055 (+)	1572	WP_019293245.1	ABC transporter permease subunit	-
J0J33_RS04645 (J0J33_04645)	-	935056..935793 (+)	738	WP_019292074.1	amino acid ABC transporter ATP-binding protein	-
J0J33_RS04650 (J0J33_04650)	murD	935933..937294 (+)	1362	WP_165719432.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56888.98 Da
• Isoelectric Point: 5.2995

>NTDB_id=544726 J0J33_RS04635 WP_019293246.1 931598..933088(+) (covS) [Lactococcus sp. LG1267]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=544726 J0J33_RS04635 WP_019293246.1 931598..933088(+) (covS) [Lactococcus sp. LG1267]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCTTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGACATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTTTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGACAAATACATTATTACAACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.823	100	0.56