Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LO740_RS22340 Genome accession   NZ_CP087294
Coordinates   4607334..4607924 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain APEC E956     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4602334..4612924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LO740_RS22325 (LO740_22275) uhpT 4602856..4604247 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  LO740_RS22330 (LO740_22280) uhpC 4604503..4605822 (-) 1320 WP_001696326.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  LO740_RS22335 (LO740_22285) uhpB 4605832..4607334 (-) 1503 WP_001318135.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  LO740_RS22340 (LO740_22290) letA 4607334..4607924 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  LO740_RS22345 (LO740_22295) ilvN 4607997..4608287 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  LO740_RS22350 (LO740_22300) ilvB 4608291..4609979 (-) 1689 WP_000168476.1 acetolactate synthase large subunit -
  LO740_RS22355 (LO740_22305) ivbL 4610085..4610183 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  LO740_RS22360 (LO740_22310) tisB 4610747..4610836 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  LO740_RS22365 (LO740_22315) ysdE 4610960..4611034 (-) 75 WP_211180519.1 protein YsdE -
  LO740_RS22370 (LO740_22320) emrD 4611116..4612300 (+) 1185 WP_001696327.1 multidrug efflux MFS transporter EmrD -
  LO740_RS22375 (LO740_22325) yidF 4612308..4612805 (-) 498 WP_000148034.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=544591 LO740_RS22340 WP_000633668.1 4607334..4607924(-) (letA) [Escherichia coli strain APEC E956]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=544591 LO740_RS22340 WP_000633668.1 4607334..4607924(-) (letA) [Escherichia coli strain APEC E956]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378