Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LO741_RS23650 Genome accession   NZ_CP087290
Coordinates   4810030..4811862 (+) Length   610 a.a.
NCBI ID   WP_187183321.1    Uniprot ID   -
Organism   Escherichia coli strain APEC 102026     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4805030..4816862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LO741_RS23615 (LO741_23570) dcyD 4805255..4806241 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  LO741_RS23620 (LO741_23575) tcyL 4806256..4806924 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LO741_RS23625 (LO741_23580) tcyN 4806921..4807673 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LO741_RS23630 (LO741_23585) sdiA 4807905..4808627 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  LO741_RS23635 (LO741_23590) yecF 4808694..4808918 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LO741_RS23640 (LO741_23595) yecU 4808905..4809081 (-) 177 WP_000590344.1 protein YecU -
  LO741_RS26720 - 4809119..4809235 (-) 117 WP_001302039.1 hypothetical protein -
  LO741_RS23645 (LO741_23600) letA 4809377..4810033 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LO741_RS23650 (LO741_23605) uvrC 4810030..4811862 (+) 1833 WP_187183321.1 excinuclease ABC subunit UvrC Machinery gene
  LO741_RS23655 (LO741_23610) pgsA 4811919..4812467 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LO741_RS23675 (LO741_23630) yecA 4813117..4813782 (+) 666 WP_000847885.1 UPF0149 family protein YecA -
  LO741_RS23680 (LO741_23635) tyrP 4813832..4815043 (-) 1212 WP_000797555.1 tyrosine transporter TyrP -
  LO741_RS23685 (LO741_23640) yecH 4815234..4815473 (+) 240 WP_000377224.1 YecH family metal-binding protein -
  LO741_RS23690 (LO741_23645) ftnA 4815511..4816008 (-) 498 WP_000917208.1 non-heme ferritin -
  LO741_RS23695 (LO741_23650) yecR 4816180..4816503 (-) 324 WP_001237876.1 YecR-like lipofamily protein -
  LO741_RS23700 (LO741_23655) azuC 4816766..4816852 (+) 87 WP_010723106.1 stress response protein AzuC -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68149.01 Da        Isoelectric Point: 9.1942

>NTDB_id=544517 LO741_RS23650 WP_187183321.1 4810030..4811862(+) (uvrC) [Escherichia coli strain APEC 102026]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSCSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDESKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=544517 LO741_RS23650 WP_187183321.1 4810030..4811862(+) (uvrC) [Escherichia coli strain APEC 102026]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCCTTTATCTTCCT
GAGTGGCGATACCCATCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCTAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATATTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGTAAAGTGCTCGGCAGCTGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATCGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCATTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAATGCTTTGACATC
AGCCATACCATGGGGGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGACG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGAGAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAACTTGCGCAGGCGAAAAATGTTTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTAGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCACTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

38.158

99.672

0.38
  uvrC Streptococcus pneumoniae R6

37.829

99.672

0.377
  uvrC Streptococcus pneumoniae D39

37.829

99.672

0.377