Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LO742_RS23795 Genome accession   NZ_CP087287
Coordinates   4809287..4809877 (-) Length   196 a.a.
NCBI ID   WP_001332271.1    Uniprot ID   A0A0H2Z4C4
Organism   Escherichia coli strain APEC 16-1068     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4804287..4814877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LO742_RS23780 (LO742_23745) uhpT 4804927..4806318 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  LO742_RS23785 (LO742_23750) uhpC 4806456..4807775 (-) 1320 WP_001350834.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  LO742_RS23790 (LO742_23755) uhpB 4807785..4809287 (-) 1503 WP_001332272.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  LO742_RS23795 (LO742_23760) letA 4809287..4809877 (-) 591 WP_001332271.1 transcriptional regulator UhpA Regulator
  LO742_RS23800 (LO742_23765) ilvN 4809950..4810240 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  LO742_RS23805 (LO742_23770) ilvB 4810244..4811932 (-) 1689 WP_000168473.1 acetolactate synthase large subunit -
  LO742_RS23810 (LO742_23775) ivbL 4812038..4812136 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  LO742_RS23815 (LO742_23780) ysdE 4812381..4812455 (-) 75 WP_211180519.1 protein YsdE -
  LO742_RS23820 (LO742_23785) emrD 4812537..4813721 (+) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  LO742_RS23825 (LO742_23790) yidF 4813729..4814226 (-) 498 WP_000148034.1 radical SAM protein -
  LO742_RS23830 (LO742_23795) yidG 4814223..4814585 (-) 363 WP_001113443.1 DUF202 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20836.26 Da        Isoelectric Point: 5.6059

>NTDB_id=544423 LO742_RS23795 WP_001332271.1 4809287..4809877(-) (letA) [Escherichia coli strain APEC 16-1068]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=544423 LO742_RS23795 WP_001332271.1 4809287..4809877(-) (letA) [Escherichia coli strain APEC 16-1068]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGTGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z4C4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378