Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LMF34_RS10130 Genome accession   NZ_CP086678
Coordinates   2114989..2115579 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain EFF60     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2109989..2120579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LMF34_RS10115 - 2111266..2111748 (+) 483 WP_038428612.1 hypothetical protein -
  LMF34_RS10120 - 2112090..2113318 (+) 1229 WP_089541817.1 IS3 family transposase -
  LMF34_RS10125 - 2113364..2114827 (+) 1464 WP_001521690.1 hypothetical protein -
  LMF34_RS10130 letA 2114989..2115579 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  LMF34_RS10135 uhpB 2115579..2117081 (+) 1503 WP_001521689.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  LMF34_RS10140 uhpC 2117091..2118410 (+) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  LMF34_RS10145 uhpT 2118666..2120057 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=544027 LMF34_RS10130 WP_000633668.1 2114989..2115579(+) (letA) [Escherichia coli strain EFF60]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=544027 LMF34_RS10130 WP_000633668.1 2114989..2115579(+) (letA) [Escherichia coli strain EFF60]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGTTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTGATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378