Detailed information    

insolico Bioinformatically predicted

Overview

Name   comZ   Type   Machinery gene
Locus tag   THEOS_RS06185 Genome accession   NC_019386
Coordinates   1186212..1187900 (+) Length   562 a.a.
NCBI ID   WP_016329469.1    Uniprot ID   K7QZJ0
Organism   Thermus oshimai JL-2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1181212..1192900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  THEOS_RS06150 (Theos_1232) - 1181543..1182529 (-) 987 WP_016329462.1 YpdA family putative bacillithiol disulfide reductase -
  THEOS_RS06155 (Theos_1233) - 1182554..1183312 (+) 759 WP_016329463.1 TerC family protein -
  THEOS_RS13040 (Theos_1234) - 1183309..1183968 (+) 660 WP_016329464.1 gp58-like family protein -
  THEOS_RS06165 (Theos_1235) pilA/pilA1 1183965..1184435 (+) 471 WP_016329465.1 GspH/FimT family protein Machinery gene
  THEOS_RS06170 (Theos_1236) - 1184490..1184957 (+) 468 WP_016329466.1 GspH/FimT family protein -
  THEOS_RS06175 (Theos_1237) pilA/pilA2 1184954..1185514 (+) 561 WP_016329467.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  THEOS_RS06180 (Theos_1238) pilA/pilA3 1185511..1186203 (+) 693 WP_016329468.1 PilW family protein Machinery gene
  THEOS_RS06185 (Theos_1239) comZ 1186212..1187900 (+) 1689 WP_016329469.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  THEOS_RS14035 (Theos_1240) - 1188131..1188505 (+) 375 WP_016329470.1 type II secretion system protein -
  THEOS_RS14320 - 1188666..1188740 (+) 75 WP_081593791.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  THEOS_RS06195 (Theos_1241) - 1188785..1189012 (+) 228 WP_051008282.1 hypothetical protein -
  THEOS_RS06200 (Theos_1242) - 1189206..1189505 (+) 300 WP_016329472.1 nucleotidyltransferase family protein -
  THEOS_RS06205 (Theos_1243) - 1189650..1190084 (+) 435 WP_016329473.1 hypothetical protein -
  THEOS_RS06210 (Theos_1244) - 1190163..1190720 (-) 558 WP_041436195.1 Uma2 family endonuclease -
  THEOS_RS06215 (Theos_1245) - 1190756..1191058 (+) 303 WP_016329475.1 nucleotidyltransferase family protein -
  THEOS_RS06220 (Theos_1246) - 1191119..1191766 (-) 648 WP_016329476.1 hypothetical protein -
  THEOS_RS06225 (Theos_1247) trpS 1191763..1192776 (-) 1014 WP_016329477.1 tryptophan--tRNA ligase -

Sequence

Protein


Download         Length: 562 a.a.        Molecular weight: 60053.92 Da        Isoelectric Point: 8.2871

>NTDB_id=54361 THEOS_RS06185 WP_016329469.1 1186212..1187900(+) (comZ) [Thermus oshimai JL-2]
MKRPKGIALVVTLSLLLLIALLVFGTFFTTQLELWITRNDTSSVQAFYAAEAGLQKYKTALFQQYVWQERTGGSPTTGGS
TVCYSSLSAGIDWNRNGTIDPNEAFTNGVMTLAQDETVVDAGGRPVGRYTVTLVRTGAPRVYTLISRGESSGAKARVQAT
LLLETPSPLNLAIFAGSGQTNKWLNGGATIRGGIYIVGDPANPDREVISSNGNFSLLNWYRLSDYGDLQNYVTEANREAQ
DLCASLRVQYGKISVGGSTQIGEPTNRVKGVFVGRGMQDITGTAVDVCTRTRGVCTEAIGGFDLSDPPSFPTLEGPGGCG
EGKSWRQCIREDAENSLRIVQGTPLPTLSWPTLAVPPAPPPSCLAAFSSATVELDGNAVDCSYTLPSGAKGGFRYTPGSP
ATLEVYGTVALEGFDLTLKRDTRYIAQTGTRKNASLAVLSKNGNRGNLTVEGTLLPNQPQGLFPEHVLGLVVEKDLYQKG
RYMAAPVYAGGTFRIVKQNVLMGSVMSNEFCTTSAGNQTSCAAGQSAEVVFVNTGANKPKALQFADRVAGRYVFQVLSYE
RR

Nucleotide


Download         Length: 1689 bp        

>NTDB_id=54361 THEOS_RS06185 WP_016329469.1 1186212..1187900(+) (comZ) [Thermus oshimai JL-2]
ATGAAAAGACCCAAAGGAATCGCCCTGGTGGTCACCCTAAGCCTCCTTCTCCTCATCGCCCTTCTGGTCTTCGGCACCTT
CTTCACCACCCAGCTGGAGCTCTGGATCACCCGGAACGACACCTCCTCCGTCCAGGCCTTCTACGCCGCGGAGGCCGGGC
TTCAGAAGTACAAGACGGCCCTCTTCCAGCAGTACGTCTGGCAGGAGCGCACCGGGGGAAGCCCCACCACGGGGGGAAGC
ACGGTCTGCTACTCCAGCCTGAGCGCGGGGATTGACTGGAACCGCAACGGCACCATAGACCCGAACGAGGCCTTCACCAA
CGGCGTCATGACCCTGGCCCAGGACGAGACCGTGGTGGACGCGGGAGGGCGCCCCGTGGGCCGGTACACCGTGACCCTGG
TGCGCACCGGCGCCCCCCGGGTCTACACCCTCATCTCCCGGGGGGAGTCCTCGGGGGCCAAGGCCCGGGTCCAGGCCACC
CTCCTCCTGGAAACCCCAAGCCCCCTCAACCTGGCCATCTTCGCGGGAAGCGGCCAGACCAACAAATGGCTGAACGGCGG
GGCCACCATCCGGGGGGGGATCTACATCGTGGGGGACCCCGCCAACCCGGACCGGGAGGTCATCTCCTCCAACGGGAACT
TCAGCCTGCTGAACTGGTACCGGCTGAGCGACTACGGCGACCTGCAGAACTACGTCACCGAGGCCAACCGCGAGGCCCAG
GACCTCTGCGCCTCCTTACGGGTGCAGTACGGGAAGATCTCCGTGGGGGGGAGCACCCAGATCGGGGAGCCCACCAACCG
GGTGAAGGGGGTCTTCGTGGGCCGGGGCATGCAGGACATCACGGGGACCGCGGTGGACGTCTGCACCCGCACCCGGGGGG
TCTGCACCGAGGCCATCGGGGGCTTTGACCTTTCCGACCCCCCAAGCTTCCCCACCCTGGAGGGCCCCGGAGGGTGCGGG
GAGGGCAAGAGCTGGCGGCAGTGCATCCGGGAGGACGCGGAAAATAGCCTCCGCATCGTCCAGGGAACCCCCTTGCCCAC
CCTGAGCTGGCCCACTTTGGCCGTCCCCCCCGCCCCGCCCCCCTCCTGCCTGGCCGCCTTTAGCTCAGCCACGGTAGAGC
TGGACGGGAACGCGGTGGACTGCTCCTACACCCTCCCCAGCGGGGCCAAGGGGGGCTTCCGGTACACCCCGGGAAGCCCG
GCCACCCTGGAGGTCTACGGCACCGTGGCCCTGGAGGGGTTTGACCTCACCCTCAAGCGGGACACCCGCTACATCGCCCA
GACAGGCACCCGCAAGAACGCCAGCCTGGCGGTGCTCAGCAAGAACGGGAACCGGGGCAACCTCACCGTGGAAGGCACCC
TCCTCCCGAACCAGCCCCAGGGCCTCTTCCCCGAGCACGTGCTGGGCCTGGTGGTGGAGAAGGACCTGTACCAGAAGGGC
CGGTACATGGCCGCCCCCGTCTACGCCGGGGGCACCTTCCGCATCGTGAAGCAGAACGTGCTCATGGGCTCCGTCATGAG
CAACGAGTTCTGCACCACCAGCGCCGGCAACCAGACGAGCTGCGCCGCGGGCCAGAGCGCCGAGGTGGTTTTCGTGAACA
CCGGGGCCAATAAGCCCAAGGCGCTGCAGTTCGCCGACCGGGTGGCGGGGCGGTACGTCTTCCAGGTGCTCTCCTATGAG
CGCCGCTAG

Domains

Predicted by InterproScan.

PilX N-terminal (PilX_N)

(5-54)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K7QZJ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comZ Thermus thermophilus HB27

58.511

100

0.587

Multiple sequence alignment