Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   THEOS_RS01225 Genome accession   NC_019386
Coordinates   230348..231340 (-) Length   330 a.a.
NCBI ID   WP_016328522.1    Uniprot ID   K7RFK4
Organism   Thermus oshimai JL-2     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 225348..236340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  THEOS_RS01200 (Theos_0239) hisG 225957..226580 (+) 624 WP_016328517.1 ATP phosphoribosyltransferase -
  THEOS_RS01205 (Theos_0240) trmH 226564..227139 (+) 576 WP_016328518.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH -
  THEOS_RS01210 (Theos_0241) - 227380..228336 (-) 957 WP_016328519.1 branched-chain amino acid transaminase -
  THEOS_RS01215 (Theos_0242) - 228369..229277 (-) 909 WP_016328520.1 LysR substrate-binding domain-containing protein -
  THEOS_RS01220 (Theos_0243) - 229381..230289 (+) 909 WP_016328521.1 manganese catalase family protein -
  THEOS_RS01225 (Theos_0244) dprA 230348..231340 (-) 993 WP_016328522.1 DNA-processing protein DprA Machinery gene
  THEOS_RS01230 (Theos_0245) era 231389..232294 (+) 906 WP_016328523.1 GTPase Era -
  THEOS_RS01235 (Theos_0246) - 232342..233223 (+) 882 WP_016328524.1 acyltransferase -
  THEOS_RS01240 (Theos_0247) - 233220..234797 (-) 1578 WP_041436053.1 HD domain-containing phosphohydrolase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 34918.35 Da        Isoelectric Point: 6.3699

>NTDB_id=54347 THEOS_RS01225 WP_016328522.1 230348..231340(-) (dprA) [Thermus oshimai JL-2]
MDPLALALLPGIGPKRLLELLLEEDPLSALRARFPQALPHLEGALARAEAERRRAEALGVRILGLWEEAFPESLKALPQP
PTHLYLKGSLESPAVALVGTRKASPWALGFARRLARALAEAGAYVVSGLARGIDREAHLGALEAGGRTLGVLGSALDRVY
PPEHQSLAERVDLLSEFPFGTGAKAEFFPRRNRLIAGLAQAVIVVEAPLDSGALITARHALELGKEVLAVPGRPTDENSL
GANRLIQDGAYPVLAPEDALSYLGLKGRPKDPGLPPEEQALYEALRKGEALPEDLAQALGLSVGEVLGLLARLELKGLAR
ALPGGRYGAG

Nucleotide


Download         Length: 993 bp        

>NTDB_id=54347 THEOS_RS01225 WP_016328522.1 230348..231340(-) (dprA) [Thermus oshimai JL-2]
ATGGACCCTCTGGCCCTGGCCCTCCTTCCGGGGATCGGCCCCAAGAGGCTCCTGGAGCTCCTTCTGGAGGAAGACCCCCT
TTCCGCCTTAAGGGCGCGCTTCCCCCAGGCCCTCCCCCACCTGGAAGGGGCCCTGGCCCGGGCCGAGGCCGAGCGCCGGC
GGGCGGAGGCCCTCGGGGTGAGGATCCTCGGCCTATGGGAAGAGGCCTTTCCCGAAAGCCTCAAGGCCCTCCCCCAGCCC
CCCACCCACCTCTACCTGAAGGGGAGCCTGGAGAGCCCCGCGGTGGCCCTGGTGGGCACCCGCAAGGCCTCCCCCTGGGC
TTTGGGCTTCGCCCGGAGGCTCGCCCGGGCCCTGGCGGAGGCCGGGGCCTACGTGGTCTCGGGGCTCGCCCGGGGGATTG
ACCGGGAGGCCCACCTGGGGGCCCTGGAGGCCGGGGGAAGGACCCTTGGGGTTTTGGGGAGCGCCCTGGACCGGGTCTAC
CCCCCGGAGCACCAGAGCCTAGCGGAAAGGGTGGACCTCCTCTCGGAGTTCCCCTTCGGCACCGGGGCCAAGGCGGAGTT
CTTCCCCCGGCGGAACCGCCTCATCGCCGGGCTCGCGCAGGCGGTCATCGTGGTGGAGGCCCCCCTGGACTCCGGGGCCC
TCATCACCGCCCGCCACGCCCTGGAGCTCGGGAAGGAGGTCCTGGCGGTGCCGGGAAGGCCCACGGACGAGAACTCCTTG
GGGGCCAACCGCCTCATCCAAGACGGGGCCTACCCGGTCCTGGCCCCCGAGGACGCCCTTTCCTACCTGGGCCTGAAGGG
GCGCCCTAAAGACCCCGGGCTTCCCCCGGAAGAACAGGCCCTCTACGAGGCCCTCCGGAAGGGAGAGGCCCTCCCCGAGG
ACCTGGCCCAGGCCCTGGGCCTTTCCGTGGGGGAGGTCTTGGGCCTCCTTGCCCGCCTCGAGCTCAAGGGCCTGGCCCGG
GCCCTGCCGGGGGGGCGGTACGGGGCAGGGTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(56-253)

DprA winged helix domain (DprA_WH)

(269-325)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K7RFK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Thermus thermophilus HB27

79.94

100

0.809
  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

39.835

100

0.439
  dprA Vibrio campbellii strain DS40M4

38.292

100

0.421
  dprA Glaesserella parasuis strain SC1401

33.962

100

0.382

Multiple sequence alignment