Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   JZI44_RS06045 Genome accession   NZ_CP071148
Coordinates   1240293..1241030 (+) Length   245 a.a.
NCBI ID   WP_012679508.1    Uniprot ID   C0M9Q1
Organism   Streptococcus equi subsp. equi strain 470_001     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1235293..1246030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZI44_RS06015 (JZI44_06015) - 1235750..1236654 (-) 905 Protein_1168 diacylglycerol kinase family protein -
  JZI44_RS06020 (JZI44_06020) - 1236764..1237414 (-) 651 WP_012515586.1 hemolysin III family protein -
  JZI44_RS06025 (JZI44_06025) - 1237398..1237853 (-) 456 WP_012515587.1 DUF1836 domain-containing protein -
  JZI44_RS06030 (JZI44_06030) - 1238114..1238869 (+) 756 WP_042356922.1 class I SAM-dependent methyltransferase -
  JZI44_RS06035 (JZI44_06035) - 1238897..1239235 (+) 339 WP_012679506.1 cupin domain-containing protein -
  JZI44_RS06040 (JZI44_06040) - 1239237..1239542 (+) 306 WP_012679507.1 hypothetical protein -
  JZI44_RS06045 (JZI44_06045) comE/blpR 1240293..1241030 (+) 738 WP_012679508.1 response regulator transcription factor Regulator
  JZI44_RS06050 (JZI44_06050) - 1241403..1241603 (+) 201 WP_012679509.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  JZI44_RS06055 (JZI44_06055) - 1241670..1242524 (+) 855 WP_012679510.1 ABC transporter ATP-binding protein -
  JZI44_RS06060 (JZI44_06060) - 1242530..1243573 (+) 1044 WP_230197352.1 ABC transporter permease subunit -
  JZI44_RS06070 (JZI44_06070) - 1244969..1245316 (+) 348 WP_042356926.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28892.31 Da        Isoelectric Point: 7.8796

>NTDB_id=543240 JZI44_RS06045 WP_012679508.1 1240293..1241030(+) (comE/blpR) [Streptococcus equi subsp. equi strain 470_001]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=543240 JZI44_RS06045 WP_012679508.1 1240293..1241030(+) (comE/blpR) [Streptococcus equi subsp. equi strain 470_001]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATATTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACCACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGCAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-240)

Response regulator receiver domain (Response_reg)

(18-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0M9Q1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.132

98.776

0.535
  comE/comE1 Streptococcus equinus JB1

45.455

98.776

0.449
  comE/comE2 Streptococcus equinus JB1

37.295

99.592

0.371