Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   JZI48_RS10725 Genome accession   NZ_CP071145
Coordinates   2236441..2237751 (-) Length   436 a.a.
NCBI ID   WP_042356911.1    Uniprot ID   -
Organism   Streptococcus equi subsp. equi strain 470_007     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2231441..2242751
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZI48_RS10690 (JZI48_10690) - 2231471..2232067 (-) 597 WP_021320719.1 methyltransferase -
  JZI48_RS10695 (JZI48_10695) coaA 2232334..2233254 (+) 921 WP_012679484.1 type I pantothenate kinase -
  JZI48_RS10700 (JZI48_10700) rpsT 2233308..2233556 (+) 249 WP_012679483.1 30S ribosomal protein S20 -
  JZI48_RS10705 (JZI48_10705) - 2233755..2234039 (-) 285 WP_012679482.1 hypothetical protein -
  JZI48_RS10710 (JZI48_10710) - 2234058..2234450 (-) 393 WP_012679481.1 hypothetical protein -
  JZI48_RS10715 (JZI48_10715) - 2234447..2235640 (-) 1194 WP_042356913.1 hypothetical protein -
  JZI48_RS10720 (JZI48_10720) - 2235637..2236056 (-) 420 WP_012679479.1 hypothetical protein -
  JZI48_RS10725 (JZI48_10725) ciaH 2236441..2237751 (-) 1311 WP_042356911.1 HAMP domain-containing sensor histidine kinase Regulator
  JZI48_RS10730 (JZI48_10730) ciaR 2237744..2238418 (-) 675 WP_012515548.1 response regulator transcription factor Regulator
  JZI48_RS10735 (JZI48_10735) - 2238837..2241374 (-) 2538 WP_012679477.1 M1 family metallopeptidase -
  JZI48_RS10740 (JZI48_10740) phoU 2241608..2242261 (-) 654 WP_012679476.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49503.13 Da        Isoelectric Point: 9.5549

>NTDB_id=543204 JZI48_RS10725 WP_042356911.1 2236441..2237751(-) (ciaH) [Streptococcus equi subsp. equi strain 470_007]
MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARARQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=543204 JZI48_RS10725 WP_042356911.1 2236441..2237751(-) (ciaH) [Streptococcus equi subsp. equi strain 470_007]
ATGAATAAACTAAAAAAAGGATTATTGTCCGATAATTATACGCATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTACAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCTAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGCCAGCTCAATAACATTG
TCACCACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTTCACATTAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAGCTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTGGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACAACTAATCTGTTAAATTTAGCCAGAAGTGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGATACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAGTCAGGCAAGCAGTTTATCTCAGTTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGGCACGCCAAAAAGGA
GGGTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGCGCCATCTTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.437

100

0.576
  ciaH Streptococcus pneumoniae Rx1

50.917

100

0.509
  ciaH Streptococcus pneumoniae D39

50.917

100

0.509
  ciaH Streptococcus pneumoniae R6

50.917

100

0.509
  ciaH Streptococcus pneumoniae TIGR4

50.917

100

0.509