Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SDSE_RS13415 Genome accession   NC_019042
Coordinates   539240..540592 (+) Length   450 a.a.
NCBI ID   WP_014612101.1    Uniprot ID   A0AB38Y2E7
Organism   Streptococcus dysgalactiae subsp. equisimilis AC-2713     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 534240..545592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDSE_RS13390 (S_dysgal_equisimilis_AC2713_603) - 535307..535954 (-) 648 WP_003057245.1 amino acid ABC transporter permease -
  SDSE_RS13395 (S_dysgal_equisimilis_AC2713_604) - 535969..536670 (-) 702 WP_015057398.1 amino acid ABC transporter permease -
  SDSE_RS13400 (S_dysgal_equisimilis_AC2713_605) - 536684..537484 (-) 801 WP_015057399.1 transporter substrate-binding domain-containing protein -
  SDSE_RS13405 (S_dysgal_equisimilis_AC2713_606) - 537484..538278 (-) 795 WP_015057400.1 amino acid ABC transporter ATP-binding protein -
  SDSE_RS13410 (S_dysgal_equisimilis_AC2713_607) vicR 538537..539247 (+) 711 WP_003057225.1 response regulator YycF Regulator
  SDSE_RS13415 (S_dysgal_equisimilis_AC2713_608) vicK 539240..540592 (+) 1353 WP_014612101.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SDSE_RS13420 (S_dysgal_equisimilis_AC2713_609) vicX 540596..541405 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  SDSE_RS13425 (S_dysgal_equisimilis_AC2713_610) - 541721..542584 (+) 864 WP_003059989.1 IS982 family transposase -
  SDSE_RS13430 (S_dysgal_equisimilis_AC2713_611) rnc 543131..543823 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51476.06 Da        Isoelectric Point: 5.7411

>NTDB_id=54298 SDSE_RS13415 WP_014612101.1 539240..540592(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=54298 SDSE_RS13415 WP_014612101.1 539240..540592(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGGTCTGGTAAAATCATCATGATTAACGAGACAGCTCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTTACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-165)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.188

92

0.673
  micB Streptococcus pneumoniae Cp1015

66.588

94.444

0.629

Multiple sequence alignment