Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   JYA46_RS02655 Genome accession   NZ_CP070991
Coordinates   472260..473234 (+) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain CBS2016-05     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 467260..478234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JYA46_RS02620 (JYA46_000524) rpmG 467720..467869 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  JYA46_RS02625 (JYA46_000525) - 468078..468617 (+) 540 WP_000164552.1 5-formyltetrahydrofolate cyclo-ligase -
  JYA46_RS02630 (JYA46_000526) - 468629..470092 (+) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  JYA46_RS02635 (JYA46_000527) - 470073..470276 (+) 204 WP_000087561.1 YqgQ family protein -
  JYA46_RS02640 (JYA46_000528) - 470273..471259 (+) 987 WP_000161315.1 ROK family glucokinase -
  JYA46_RS02645 (JYA46_000529) - 471259..471588 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  JYA46_RS02650 (JYA46_000530) - 471585..472208 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  JYA46_RS02655 (JYA46_000531) comGA 472260..473234 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  JYA46_RS02660 (JYA46_000532) comGB 473206..474276 (+) 1071 WP_000776418.1 competence type IV pilus assembly protein ComGB Machinery gene
  JYA46_RS02665 (JYA46_000533) comGC 474290..474601 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  JYA46_RS02670 (JYA46_000534) comGD 474579..475025 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  JYA46_RS02675 (JYA46_000535) comGE 475012..475311 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  JYA46_RS02680 (JYA46_000536) comGF 475229..475687 (+) 459 WP_072491748.1 competence type IV pilus minor pilin ComGF Machinery gene
  JYA46_RS02685 (JYA46_000537) - 475784..475930 (+) 147 WP_001789879.1 hypothetical protein -
  JYA46_RS02690 (JYA46_000538) - 475920..476444 (+) 525 WP_210994247.1 shikimate kinase -
  JYA46_RS02695 (JYA46_000539) gcvT 476603..477694 (+) 1092 WP_072491749.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=541966 JYA46_RS02655 WP_000697220.1 472260..473234(+) (comGA) [Staphylococcus aureus strain CBS2016-05]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=541966 JYA46_RS02655 WP_000697220.1 472260..473234(+) (comGA) [Staphylococcus aureus strain CBS2016-05]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTAATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCTACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCCATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1