Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   JYA46_RS02660 Genome accession   NZ_CP070991
Coordinates   473206..474276 (+) Length   356 a.a.
NCBI ID   WP_000776418.1    Uniprot ID   -
Organism   Staphylococcus aureus strain CBS2016-05     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 468206..479276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JYA46_RS02630 (JYA46_000526) - 468629..470092 (+) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  JYA46_RS02635 (JYA46_000527) - 470073..470276 (+) 204 WP_000087561.1 YqgQ family protein -
  JYA46_RS02640 (JYA46_000528) - 470273..471259 (+) 987 WP_000161315.1 ROK family glucokinase -
  JYA46_RS02645 (JYA46_000529) - 471259..471588 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  JYA46_RS02650 (JYA46_000530) - 471585..472208 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  JYA46_RS02655 (JYA46_000531) comGA 472260..473234 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  JYA46_RS02660 (JYA46_000532) comGB 473206..474276 (+) 1071 WP_000776418.1 competence type IV pilus assembly protein ComGB Machinery gene
  JYA46_RS02665 (JYA46_000533) comGC 474290..474601 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  JYA46_RS02670 (JYA46_000534) comGD 474579..475025 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  JYA46_RS02675 (JYA46_000535) comGE 475012..475311 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  JYA46_RS02680 (JYA46_000536) comGF 475229..475687 (+) 459 WP_072491748.1 competence type IV pilus minor pilin ComGF Machinery gene
  JYA46_RS02685 (JYA46_000537) - 475784..475930 (+) 147 WP_001789879.1 hypothetical protein -
  JYA46_RS02690 (JYA46_000538) - 475920..476444 (+) 525 WP_210994247.1 shikimate kinase -
  JYA46_RS02695 (JYA46_000539) gcvT 476603..477694 (+) 1092 WP_072491749.1 glycine cleavage system aminomethyltransferase GcvT -
  JYA46_RS02700 (JYA46_000540) gcvPA 477714..479060 (+) 1347 WP_000019687.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41461.91 Da        Isoelectric Point: 10.1030

>NTDB_id=541967 JYA46_RS02660 WP_000776418.1 473206..474276(+) (comGB) [Staphylococcus aureus strain CBS2016-05]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNKLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=541967 JYA46_RS02660 WP_000776418.1 473206..474276(+) (comGB) [Staphylococcus aureus strain CBS2016-05]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGCACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAGATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATCATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATTTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATCCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAGTTAATTTACAACAAATTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAATTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.719

100

0.997
  comGB Staphylococcus aureus N315

99.719

100

0.997