Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JYA46_RS00515 Genome accession   NZ_CP070991
Coordinates   92592..93221 (+) Length   209 a.a.
NCBI ID   WP_072491830.1    Uniprot ID   -
Organism   Staphylococcus aureus strain CBS2016-05     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 87592..98221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JYA46_RS00490 (JYA46_000098) - 88032..89018 (-) 987 WP_000999713.1 aromatic acid exporter family protein -
  JYA46_RS00495 (JYA46_000099) map 89485..90243 (+) 759 WP_061732059.1 type I methionyl aminopeptidase -
  JYA46_RS00500 (JYA46_000100) - 90460..90846 (+) 387 WP_210994220.1 hypothetical protein -
  JYA46_RS00505 (JYA46_000101) liaF 90861..91562 (+) 702 WP_098818122.1 cell wall-active antibiotics response protein LiaF -
  JYA46_RS00510 (JYA46_000102) vraS 91559..92602 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  JYA46_RS00515 (JYA46_000103) vraR 92592..93221 (+) 630 WP_072491830.1 two-component system response regulator VraR Regulator
  JYA46_RS00520 (JYA46_000104) - 93334..94551 (-) 1218 WP_210994221.1 YihY/virulence factor BrkB family protein -
  JYA46_RS00525 (JYA46_000105) - 94829..95104 (-) 276 WP_072491832.1 YtxH domain-containing protein -
  JYA46_RS00530 (JYA46_000106) - 95111..95575 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  JYA46_RS00535 (JYA46_000107) - 95722..95922 (+) 201 WP_000180460.1 DUF1128 family protein -
  JYA46_RS00540 (JYA46_000108) - 95925..97181 (+) 1257 WP_001793428.1 aminopeptidase -
  JYA46_RS00545 (JYA46_000109) - 97271..97801 (+) 531 WP_000184381.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23575.38 Da        Isoelectric Point: 5.3889

>NTDB_id=541955 JYA46_RS00515 WP_072491830.1 92592..93221(+) (vraR) [Staphylococcus aureus strain CBS2016-05]
MTIKVLFVDDHEMVRIGISSYLSMQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=541955 JYA46_RS00515 WP_072491830.1 92592..93221(+) (vraR) [Staphylococcus aureus strain CBS2016-05]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAATGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373