Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   LL046_RS08305 Genome accession   NZ_CP086088
Coordinates   1673070..1674437 (-) Length   455 a.a.
NCBI ID   WP_017864854.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain EIP13A     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1668070..1679437
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL046_RS08290 (LL046_08270) - 1669241..1670674 (-) 1434 WP_017864852.1 6-phospho-beta-glucosidase -
  LL046_RS08295 (LL046_08275) yidD 1670797..1671063 (-) 267 WP_012898265.1 membrane protein insertion efficiency factor YidD -
  LL046_RS08300 (LL046_08280) - 1671180..1672922 (-) 1743 WP_017864853.1 1-deoxy-D-xylulose-5-phosphate synthase -
  LL046_RS08305 (LL046_08285) ciaH 1673070..1674437 (-) 1368 WP_017864854.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LL046_RS08310 (LL046_08290) ciaR 1674531..1675199 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  LL046_RS08315 (LL046_08295) - 1675377..1676351 (-) 975 WP_003130365.1 LacI family DNA-binding transcriptional regulator -
  LL046_RS08320 (LL046_08300) - 1676504..1678759 (-) 2256 WP_003130366.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 51200.75 Da        Isoelectric Point: 9.4771

>NTDB_id=540290 LL046_RS08305 WP_017864854.1 1673070..1674437(-) (ciaH) [Lactococcus lactis subsp. lactis strain EIP13A]
MKKIIKKIKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLEEAANNQLGTSSSQD
SGFGPNNSVIFYDSEGKNFMPSTGSNANISTNFGMSLLQKAMKFNEKHINTIQTVSVKNPYGDNLHYRYYTTSQFIITNS
DGTVTPVYMQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSIIISLYLANWTLRPILAAYEKQKEFVENASHELRTPLAIL
QNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKFS
GHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKARTR
QKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=540290 LL046_RS08305 WP_017864854.1 1673070..1674437(-) (ciaH) [Lactococcus lactis subsp. lactis strain EIP13A]
TTGAAGAAAATAATTAAAAAAATTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTGTTTTTGGAAGAAGCAGCGAATAATCAATTAGGAACAAGTAGTTCACAAGAC
AGTGGCTTTGGACCTAATAATAGTGTAATTTTTTATGATTCAGAAGGAAAAAACTTTATGCCGTCAACGGGCTCAAATGC
AAATATAAGTACAAACTTTGGCATGAGTCTTTTGCAAAAAGCAATGAAATTTAATGAAAAACATATAAATACAATTCAGA
CAGTATCTGTAAAAAATCCTTATGGAGATAATTTGCACTATCGTTATTACACAACATCGCAATTTATCATTACAAATTCT
GATGGTACTGTGACGCCAGTTTATATGCAAATTTTTTCAAACGTTGACCAAATTCAAGATGCCATGAGTCGTGCCATGTG
GGTCATTGTGACAACAATGATTACTTTCTGGCTACTATCAATAATTATTAGTTTGTATCTTGCAAATTGGACATTAAGAC
CTATTCTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATCTTG
CAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACTGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTTATC
TGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGCCAG
AGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTTTCA
GGCCATTTGAAATTAGATGGAACGATTAATTTGGATCAAGCCCTGATTAAACAATTGCTGACCATCTTATTTGATAATGC
TCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCGCCG
ATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACGCGT
CAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGAAGA
TAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGACAGCACAATTTCAAATCCTGCAAAAATTTTCCAAA
AGTTGTAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(222-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-441)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.372

94.505

0.457
  ciaH Streptococcus pneumoniae Rx1

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae D39

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae R6

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae TIGR4

44.444

98.901

0.44