Detailed information NTG0540108

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: LL047_RS08880
• Genome accession: NZ_CP086072
• Coordinates: 1750711..1752081 (-)
• Length: 456 a.a.
• NCBI ID: WP_010906089.1
• Uniprot ID: Q9CF07
• Organism: Lactococcus lactis subsp. lactis strain EIP33
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 1745711..1757081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL047_RS08860 (LL047_08840)	-	1746201..1746623 (-)	423	Protein_1723	YhgE/Pip domain-containing protein	-
LL047_RS08865 (LL047_08845)	-	1746882..1748315 (-)	1434	WP_010906086.1	6-phospho-beta-glucosidase	-
LL047_RS08870 (LL047_08850)	yidD	1748438..1748704 (-)	267	WP_010906087.1	membrane protein insertion efficiency factor YidD	-
LL047_RS08875 (LL047_08855)	-	1748821..1750563 (-)	1743	WP_010906088.1	1-deoxy-D-xylulose-5-phosphate synthase	-
LL047_RS08880 (LL047_08860)	ciaH	1750711..1752081 (-)	1371	WP_010906089.1	cell wall metabolism sensor histidine kinase WalK	Regulator
LL047_RS08885 (LL047_08865)	ciaR	1752174..1752842 (-)	669	WP_021722129.1	response regulator transcription factor	Regulator
LL047_RS08890 (LL047_08870)	-	1753020..1753994 (-)	975	WP_003130365.1	LacI family DNA-binding transcriptional regulator	-
LL047_RS08895 (LL047_08875)	-	1754147..1756402 (-)	2256	WP_010906090.1	glycoside hydrolase family 65 protein	-

Sequence

Protein

• Length: 456 a.a.
• Molecular weight: 51278.80 Da
• Isoelectric Point: 9.3135

>NTDB_id=540108 LL047_RS08880 WP_010906089.1 1750711..1752081(-) (ciaH) [Lactococcus lactis subsp. lactis strain EIP33]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGDLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide

• Length: 1371 bp

>NTDB_id=540108 LL047_RS08880 WP_010906089.1 1750711..1752081(-) (ciaH) [Lactococcus lactis subsp. lactis strain EIP33]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAATTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAACACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTAA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCGATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTAACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (333-442)

• His Kinase A (phospho-acceptor) domain (HisKA) (223-289)

3D structure

• AlphaFold DB: Q9CF07

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	48.837	94.298	0.461
ciaH	Streptococcus pneumoniae Rx1	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae D39	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae R6	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae TIGR4	44.321	98.465	0.436