Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LJX82_RS19155 Genome accession   NZ_CP085638
Coordinates   3975563..3976222 (-) Length   219 a.a.
NCBI ID   WP_001221502.1    Uniprot ID   B7LGG8
Organism   Escherichia coli strain fEC.1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3970563..3981222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LJX82_RS19130 (LJX82_19130) parE 3970654..3972546 (+) 1893 WP_063112571.1 DNA topoisomerase IV subunit B -
  LJX82_RS19135 (LJX82_19135) ygiN 3972594..3972908 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  LJX82_RS19140 (LJX82_19140) mdaB 3972939..3973520 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  LJX82_RS19145 (LJX82_19145) ygiZ 3973839..3974171 (+) 333 WP_000912120.1 DUF2645 family protein -
  LJX82_RS19150 (LJX82_19150) qseC 3974217..3975566 (-) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  LJX82_RS19155 (LJX82_19155) ciaR 3975563..3976222 (-) 660 WP_001221502.1 quorum sensing response regulator transcription factor QseB Regulator
  LJX82_RS19160 (LJX82_19160) ygiW 3976374..3976766 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  LJX82_RS19165 (LJX82_19165) ygiV 3976819..3977301 (+) 483 WP_000183494.1 AraC family transcriptional regulator -
  LJX82_RS19170 (LJX82_19170) parC 3977847..3980105 (+) 2259 WP_001281841.1 DNA topoisomerase IV subunit A -
  LJX82_RS19175 (LJX82_19175) plsC 3980339..3981076 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6543

>NTDB_id=538802 LJX82_RS19155 WP_001221502.1 3975563..3976222(-) (ciaR) [Escherichia coli strain fEC.1]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=538802 LJX82_RS19155 WP_001221502.1 3975563..3976222(-) (ciaR) [Escherichia coli strain fEC.1]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAAGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7LGG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365