Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SPB_RS10295 Genome accession   NZ_AEUT02000001
Coordinates   2036654..2038630 (+) Length   658 a.a.
NCBI ID   WP_003102604.1    Uniprot ID   -
Organism   Streptococcus parauberis NCFD 2020     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2031654..2043630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPB_RS10280 (SPB_2121) argR 2033247..2033684 (+) 438 WP_003105697.1 arginine repressor -
  SPB_RS10285 (SPB_2122) - 2033681..2034034 (+) 354 WP_003104802.1 YlbF family regulator -
  SPB_RS10290 (SPB_2123) hexA 2034021..2036576 (+) 2556 WP_003105604.1 DNA mismatch repair protein MutS Machinery gene
  SPB_RS10295 (SPB_2124) hexB 2036654..2038630 (+) 1977 WP_003102604.1 DNA mismatch repair endonuclease MutL Machinery gene
  SPB_RS10300 (SPB_2125) - 2038641..2039864 (+) 1224 WP_003103803.1 MFS transporter -
  SPB_RS10305 (SPB_2126) ruvA 2039866..2040459 (+) 594 WP_003103584.1 Holliday junction branch migration protein RuvA Machinery gene
  SPB_RS10310 (SPB_2127) - 2040463..2041014 (+) 552 WP_003104649.1 DNA-3-methyladenine glycosylase I -
  SPB_RS10315 (SPB_2128) cinA 2041403..2042674 (+) 1272 WP_003103228.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 73913.26 Da        Isoelectric Point: 5.1374

>NTDB_id=53863 SPB_RS10295 WP_003102604.1 2036654..2038630(+) (hexB) [Streptococcus parauberis NCFD 2020]
MQKIVELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQITIEIEESGLKSITITDNGDGMSKEDLPLSLLRHATSK
IKNQSDLFRIRTLGFRGEALPSIASISLLTIKSATAEADYGNQLISKGGEVESIEPVSTPVGTKIKVENLFFNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLICDGRELTKTSGTADLKQAIAGIYGINTAKKMVEISTADLDFEVSGFVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISS
AISESLRLQDLIPDALENLAKSTTRNNNKFEQTSLPLQANKIYYDKEKGDFFTVDNRKEEPSNQPGQSNIVDSGVKIGDQ
VPPLVEETSPTFSVKHASRTISDVDDANHPDLDLSNQKKLTKLIENLENEETSVFPELDYFGQMHGTYLFAQGNGGLFII
DQHAAQERVKYEYYREKIGQVDNSLQQLLVPYLFEFSGSDFINLQEKMDLLNQVGIYLEEYGQNTFILREHPIWMKENEI
ESGVYEMCDMLLLTNNVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYNCPHGRPVLINFSKADMEK
MFRRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=53863 SPB_RS10295 WP_003102604.1 2036654..2038630(+) (hexB) [Streptococcus parauberis NCFD 2020]
ATGCAAAAGATTGTAGAATTACCAGAGGTTCTCGCCAATCAGATCGCGGCTGGTGAAGTTATTGAACGGCCAGCAAGTGT
TGTGAAAGAATTGGTCGAGAATGCTATTGATGCCAAAAGCAGTCAAATTACAATTGAGATTGAAGAATCAGGACTTAAAT
CAATTACTATAACTGATAATGGGGATGGGATGTCAAAAGAAGACTTACCCCTTAGTTTGTTACGTCATGCAACCAGTAAG
ATAAAAAATCAAAGTGATCTTTTCAGAATTAGAACTTTGGGTTTCCGTGGTGAGGCTTTACCTTCAATTGCTTCTATCAG
TTTACTGACAATTAAATCAGCAACAGCTGAAGCAGACTATGGCAATCAACTAATCTCCAAGGGTGGAGAAGTTGAATCAA
TTGAACCAGTCTCAACGCCAGTTGGAACAAAGATAAAAGTTGAAAATCTCTTTTTCAACACGCCTGCTCGTTTAAAATAC
ATGAAGAGTCTGCAAGCTGAGCTTGCGCATATTGTCGATGTGGTCAATCGTCTTAGCTTAGCTCATCCAGAAGTAGCCTT
TACATTGATTTGTGATGGAAGGGAGTTAACTAAGACCTCAGGAACTGCTGATTTAAAACAAGCTATTGCAGGTATCTATG
GTATTAACACTGCGAAGAAAATGGTCGAGATTTCAACGGCAGATTTAGACTTTGAGGTTTCGGGCTTTGTTAGTTTACCC
GAATTAACAAGGGCAAATCGAAATTACATAACTATTTTAATCAATGGGCGTTATATCAAAAACTTTCTCTTGAACAGGGC
AATTTTAGATGGTTATGGATCAAAATTAATGGTTGGACGCTTTCCAATTGTCGTTATTGATATTCAAATCGATCCTTATT
TAGCTGATGTAAACGTCCACCCAACTAAACAGGAAGTGCGGATTTCAAAAGAACGTGAATTAATGAGTTTAATTAGTTCA
GCAATTTCAGAGAGTCTCCGTTTACAGGATTTGATTCCTGATGCCTTGGAAAATTTAGCCAAGTCAACGACAAGAAACAA
TAATAAATTTGAACAAACAAGTCTACCTTTACAAGCCAATAAAATTTACTATGATAAAGAAAAAGGTGATTTCTTTACAG
TTGATAATAGAAAAGAAGAGCCCTCTAACCAACCTGGTCAAAGTAATATAGTTGACAGCGGTGTAAAGATAGGTGACCAA
GTACCGCCTTTAGTTGAAGAGACAAGTCCAACATTCTCTGTCAAGCATGCTAGTCGCACGATAAGTGATGTGGATGATGC
CAATCATCCAGATTTGGATTTATCTAATCAGAAAAAATTAACAAAACTGATTGAAAATTTAGAGAACGAAGAAACTTCGG
TTTTCCCCGAGTTAGATTACTTTGGGCAAATGCATGGAACATATCTCTTTGCTCAGGGGAATGGTGGATTGTTTATCATT
GATCAACACGCTGCTCAAGAGCGTGTTAAATATGAGTATTATCGAGAAAAAATTGGTCAGGTCGACAATAGTTTGCAACA
ATTATTAGTTCCCTATCTCTTTGAATTTTCTGGGTCAGATTTTATTAATCTGCAAGAAAAGATGGATTTACTAAATCAAG
TTGGCATTTATCTAGAAGAATATGGACAAAATACCTTCATTCTCCGCGAACATCCAATTTGGATGAAGGAAAATGAAATT
GAATCTGGTGTCTATGAAATGTGTGATATGCTTTTGTTGACAAATAATGTGTCCATTAAAACTTATCGTGCAGAGTTAGC
CATCATGATGAGCTGTAAACGATCAATTAAAGCAAATCATAGTCTAGATGACTATTCAGCACGGCAATTACTATTGCAAC
TGGCACAATGTAAAAATCCATATAACTGTCCACATGGGCGACCTGTCTTGATTAATTTTAGTAAAGCGGATATGGAAAAA
ATGTTCCGACGGATACAAGAAAATCATACTAGCTTGAGAGATTTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(460-602)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-120)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.12

100

0.688

Multiple sequence alignment