Detailed information NTG0053862

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SPB_RS10290
• Genome accession: NZ_AEUT02000001
• Coordinates: 2034021..2036576 (+)
• Length: 851 a.a.
• NCBI ID: WP_003105604.1
• Uniprot ID: -
• Organism: Streptococcus parauberis NCFD 2020
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2029021..2041576

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPB_RS10265 (SPB_2117)	-	2029424..2030302 (+)	879	WP_003102526.1	YitT family protein	-
SPB_RS10270 (SPB_2118)	-	2030358..2031236 (+)	879	WP_003102528.1	YitT family protein	-
SPB_RS10275 (SPB_2119)	argS	2031272..2032960 (-)	1689	WP_003104213.1	arginine--tRNA ligase	-
SPB_RS10280 (SPB_2121)	argR	2033247..2033684 (+)	438	WP_003105697.1	arginine repressor	-
SPB_RS10285 (SPB_2122)	-	2033681..2034034 (+)	354	WP_003104802.1	YlbF family regulator	-
SPB_RS10290 (SPB_2123)	hexA	2034021..2036576 (+)	2556	WP_003105604.1	DNA mismatch repair protein MutS	Machinery gene
SPB_RS10295 (SPB_2124)	hexB	2036654..2038630 (+)	1977	WP_003102604.1	DNA mismatch repair endonuclease MutL	Machinery gene
SPB_RS10300 (SPB_2125)	-	2038641..2039864 (+)	1224	WP_003103803.1	MFS transporter	-
SPB_RS10305 (SPB_2126)	ruvA	2039866..2040459 (+)	594	WP_003103584.1	Holliday junction branch migration protein RuvA	Machinery gene
SPB_RS10310 (SPB_2127)	-	2040463..2041014 (+)	552	WP_003104649.1	DNA-3-methyladenine glycosylase I	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95440.94 Da
• Isoelectric Point: 4.8744

>NTDB_id=53862 SPB_RS10290 WP_003105604.1 2034021..2036576(+) (hexA) [Streptococcus parauberis NCFD 2020]
MTEPKVSPGMQQYLDIKVNYPDAFLLFRMGDFYELFYDDAVKAAQILEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
EQGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSAKPTSSNNFLVAIDYNGSNYGLAYMDLATGEFFVTALEDFAS
ICSEILNLKAKEVLVGYDLSGQEEEILVKQYNLLLSYEEEEIDDSKLLDNNLSIIEKMVASKLLAYVHHTQMRDLIHLQK
VVHYEINDYLQMSYATKSSLDLLENARTGKKHGSLYWLLDQTKTAMGMRLLRAWIDRPLISKEAVIQRQEIIQVLLDNFI
ERSDLSDSLKGVYDIERLSSRVSFGKVNPKDLLQLGHTLAQVPTIKAILESMDSPHLEGLIAGIDPIPELEHLIQSAIDP
DAPATISEGNIIKTGFDKQLDHYRKVMKEGTGWIADIEMKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTTELAKIEGQMLEAREESSTLEYDIFMQLRSRVENYIDRLQQLAKSIAAVDVLQSLAVVAEKNHYIRPSFT
DHQEINIINGRHAVVEKVMSVKEYIPNTIQFSQETNIQLITGPNMSGKSTYMRQLALTSIMAQLGSYVAADLAEIPIFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKGASPRSLILFDELGRGTATYDGMALAQSIIEFIHDHVGAKTMFATHYHEL
TDLSSRLKSLTNVHVATLEENGEVTFLHKIAQGPADKSYGIHVAKIAGLPKELLQRADAILQKLENQSTQLTLVANAEES
QQAQTDKNQQLELFAPDAEENQVIEQLKAMDVINMTPMEAMTALYELKKNL

Nucleotide

• Length: 2556 bp

>NTDB_id=53862 SPB_RS10290 WP_003105604.1 2034021..2036576(+) (hexA) [Streptococcus parauberis NCFD 2020]
ATGACAGAGCCTAAAGTTTCTCCTGGAATGCAACAGTATCTGGACATAAAAGTAAATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTACGAATTATTTTATGACGATGCTGTTAAAGCAGCTCAAATATTAGAAATTGGTTTAACCAGTC
GCAACAAGAATGCTGAAAACCCAATACCCATGGCGGGAGTGCCCCACCATTCAGCACAACAATATATTGATGTTTTAATT
GAGCAAGGTTATAAAGTAGCCATTGCTGAACAAATGGAAGATCCTAAAAAAGCTGTCGGCGTTGTTAAACGTGAAGTGGT
TCAAGTGATTACTCCCGGAACTGTTGTCGATTCAGCTAAACCAACCAGTTCAAATAATTTCTTAGTTGCGATTGATTATA
ATGGTAGCAATTATGGTTTGGCTTATATGGACCTAGCTACTGGTGAATTCTTTGTGACAGCTCTGGAGGATTTCGCAAGT
ATTTGCAGTGAAATCTTAAATTTGAAAGCTAAAGAAGTTCTTGTTGGATATGACTTAAGTGGCCAAGAAGAAGAAATTTT
AGTAAAACAATATAATCTATTACTATCTTATGAAGAGGAAGAAATTGATGACAGTAAACTTTTAGATAATAATTTGTCAA
TCATTGAAAAAATGGTCGCAAGTAAGTTATTAGCTTATGTACACCATACGCAAATGCGCGACCTAATTCACCTTCAAAAA
GTCGTTCACTATGAGATAAACGATTACTTACAAATGTCTTATGCTACTAAATCAAGCTTAGATCTACTAGAAAATGCTCG
AACCGGAAAAAAACATGGCAGTCTATACTGGTTATTAGATCAAACCAAGACAGCAATGGGGATGCGACTTCTGCGTGCTT
GGATTGACCGTCCTCTAATTAGTAAAGAAGCTGTAATCCAGCGCCAAGAAATTATTCAAGTCTTACTTGATAATTTCATT
GAGCGTTCTGATTTAAGTGATAGCTTAAAAGGTGTCTATGACATTGAAAGACTTTCAAGTCGTGTATCTTTCGGTAAGGT
TAATCCCAAAGACTTATTGCAACTAGGACATACCTTAGCTCAAGTGCCAACAATTAAAGCCATTTTGGAAAGTATGGATA
GTCCTCACTTAGAGGGACTCATTGCTGGTATCGACCCAATCCCTGAGTTAGAACACCTAATTCAATCAGCTATTGATCCA
GATGCGCCTGCAACAATTAGTGAAGGTAATATCATCAAAACTGGTTTTGACAAACAATTGGATCATTATCGGAAGGTCAT
GAAAGAAGGCACGGGCTGGATAGCAGACATTGAAATGAAAGAGCGCCAAGCAAGTGGTATTAACAATCTTAAAATTGATT
ACAATAAAAAAGATGGTTACTATTTCCATGTCACAAACTCTAATTTATCCCTTGTTCCGGACCATTTCTTTAGGAAAGCA
ACCTTAAAAAATTCTGAGCGTTATGGAACCACGGAATTAGCTAAAATTGAAGGACAAATGTTGGAAGCTAGAGAAGAATC
CTCAACTCTTGAGTACGATATCTTTATGCAATTGCGCTCACGGGTGGAAAATTATATTGATCGCCTTCAACAACTTGCCA
AATCAATTGCTGCCGTCGATGTCCTCCAAAGTTTAGCAGTTGTGGCTGAGAAAAACCATTACATCAGACCAAGTTTCACC
GACCATCAAGAAATTAATATCATTAATGGTCGCCATGCAGTGGTTGAAAAAGTGATGAGCGTCAAAGAATATATTCCCAA
CACCATTCAATTTAGTCAAGAAACGAATATCCAGCTCATTACAGGACCTAATATGAGTGGTAAATCAACTTATATGAGGC
AGTTAGCTTTAACCAGTATTATGGCCCAACTTGGTTCTTATGTGGCAGCAGACCTTGCAGAAATTCCCATTTTTGATGCC
ATCTTTACAAGAATTGGCGCAGCAGATGACCTGATTTCTGGACAATCGACATTCATGGTCGAAATGATGGAGGCCAACCA
AGCAATCAAAGGCGCAAGCCCACGGTCTTTAATTCTATTTGACGAATTAGGAAGAGGAACAGCTACTTATGATGGCATGG
CGCTAGCTCAATCAATTATTGAGTTTATCCATGACCACGTGGGAGCAAAAACAATGTTTGCCACCCATTATCATGAGTTG
ACAGACCTGTCAAGCCGCCTAAAAAGCCTGACAAATGTCCATGTCGCAACCTTGGAAGAAAATGGCGAAGTGACTTTCCT
TCATAAGATTGCCCAAGGACCGGCGGATAAATCCTACGGCATCCACGTGGCCAAAATTGCTGGGCTGCCAAAAGAACTCT
TACAACGTGCGGATGCCATTCTCCAAAAATTAGAGAACCAATCGACTCAGTTGACACTAGTTGCCAATGCAGAGGAATCC
CAACAAGCACAGACCGACAAGAATCAACAATTGGAACTCTTTGCCCCAGATGCTGAGGAGAACCAAGTCATTGAGCAATT
GAAAGCCATGGATGTTATCAATATGACCCCAATGGAGGCTATGACTGCCCTCTATGAACTGAAAAAGAACTTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-238)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	70.838	99.53	0.705
mutS	Pseudomonas stutzeri strain ATCC 17587	36.583	100	0.375