Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6K94_RS10225 Genome accession   NZ_CP069954
Coordinates   2176181..2176810 (+) Length   209 a.a.
NCBI ID   WP_194087121.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain FDAARGOS_1364     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2171181..2181810
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K94_RS10195 (I6K94_10195) - 2171286..2171822 (+) 537 WP_002494124.1 hypothetical protein -
  I6K94_RS10200 (I6K94_10200) - 2171973..2172959 (-) 987 WP_002494125.1 aromatic acid exporter family protein -
  I6K94_RS10205 (I6K94_10205) map 2173133..2173888 (+) 756 WP_002494126.1 type I methionyl aminopeptidase -
  I6K94_RS10210 (I6K94_10210) - 2174046..2174432 (+) 387 WP_001830382.1 hypothetical protein -
  I6K94_RS10215 (I6K94_10215) liaF 2174447..2175148 (+) 702 WP_002473931.1 cell wall-active antibiotics response protein LiaF -
  I6K94_RS10220 (I6K94_10220) vraS 2175145..2176191 (+) 1047 WP_002494127.1 sensor histidine kinase Regulator
  I6K94_RS10225 (I6K94_10225) vraR 2176181..2176810 (+) 630 WP_194087121.1 two-component system response regulator VraR Regulator
  I6K94_RS10230 (I6K94_10230) - 2176867..2178045 (-) 1179 WP_001830411.1 YihY/virulence factor BrkB family protein -
  I6K94_RS10235 (I6K94_10235) - 2178452..2178736 (-) 285 WP_002473916.1 YtxH domain-containing protein -
  I6K94_RS10240 (I6K94_10240) - 2178744..2179208 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  I6K94_RS10245 (I6K94_10245) - 2179349..2179564 (+) 216 WP_002494128.1 DUF1128 domain-containing protein -
  I6K94_RS10250 (I6K94_10250) - 2179566..2180807 (+) 1242 WP_017465013.1 aminopeptidase -
  I6K94_RS10255 (I6K94_10255) - 2180887..2181417 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23568.24 Da        Isoelectric Point: 4.7964

>NTDB_id=537571 I6K94_RS10225 WP_194087121.1 2176181..2176810(+) (vraR) [Staphylococcus epidermidis strain FDAARGOS_1364]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVVATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=537571 I6K94_RS10225 WP_194087121.1 2176181..2176810(+) (vraR) [Staphylococcus epidermidis strain FDAARGOS_1364]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACTCAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAAGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGTAGCAACTACTGAAATTAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAGGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCCTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTTCAAGATCGAACACAAGCAGTAATCTATGCGTTCCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368