Detailed information NTG0537570

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6K94_RS10220
• Genome accession: NZ_CP069954
• Coordinates: 2175145..2176191 (+)
• Length: 348 a.a.
• NCBI ID: WP_002494127.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain FDAARGOS_1364
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2170145..2181191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K94_RS10195 (I6K94_10195)	-	2171286..2171822 (+)	537	WP_002494124.1	hypothetical protein	-
I6K94_RS10200 (I6K94_10200)	-	2171973..2172959 (-)	987	WP_002494125.1	aromatic acid exporter family protein	-
I6K94_RS10205 (I6K94_10205)	map	2173133..2173888 (+)	756	WP_002494126.1	type I methionyl aminopeptidase	-
I6K94_RS10210 (I6K94_10210)	-	2174046..2174432 (+)	387	WP_001830382.1	hypothetical protein	-
I6K94_RS10215 (I6K94_10215)	liaF	2174447..2175148 (+)	702	WP_002473931.1	cell wall-active antibiotics response protein LiaF	-
I6K94_RS10220 (I6K94_10220)	vraS	2175145..2176191 (+)	1047	WP_002494127.1	sensor histidine kinase	Regulator
I6K94_RS10225 (I6K94_10225)	vraR	2176181..2176810 (+)	630	WP_194087121.1	two-component system response regulator VraR	Regulator
I6K94_RS10230 (I6K94_10230)	-	2176867..2178045 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
I6K94_RS10235 (I6K94_10235)	-	2178452..2178736 (-)	285	WP_002473916.1	YtxH domain-containing protein	-
I6K94_RS10240 (I6K94_10240)	-	2178744..2179208 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
I6K94_RS10245 (I6K94_10245)	-	2179349..2179564 (+)	216	WP_002494128.1	DUF1128 domain-containing protein	-
I6K94_RS10250 (I6K94_10250)	-	2179566..2180807 (+)	1242	WP_017465013.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 39994.42 Da
• Isoelectric Point: 6.0544

>NTDB_id=537570 I6K94_RS10220 WP_002494127.1 2175145..2176191(+) (vraS) [Staphylococcus epidermidis strain FDAARGOS_1364]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQGDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=537570 I6K94_RS10220 WP_002494127.1 2175145..2176191(+) (vraS) [Staphylococcus epidermidis strain FDAARGOS_1364]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACGGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ACATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGGGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92