Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I6K94_RS09755 Genome accession   NZ_CP069954
Coordinates   2087623..2088339 (-) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain FDAARGOS_1364     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2082623..2093339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K94_RS09740 (I6K94_09740) - 2083904..2084857 (+) 954 WP_001830022.1 LacI family DNA-binding transcriptional regulator -
  I6K94_RS09745 (I6K94_09745) - 2085117..2086589 (+) 1473 WP_001830011.1 sucrose-6-phosphate hydrolase -
  I6K94_RS09750 (I6K94_09750) - 2086596..2087555 (+) 960 WP_002485130.1 carbohydrate kinase -
  I6K94_RS09755 (I6K94_09755) agrA 2087623..2088339 (-) 717 WP_001829999.1 LytTR family DNA-binding domain-containing protein Regulator
  I6K94_RS09760 (I6K94_09760) - 2088356..2089645 (-) 1290 WP_204982894.1 GHKL domain-containing protein -
  I6K94_RS09765 (I6K94_09765) - 2089670..2089810 (-) 141 WP_002447513.1 cyclic lactone autoinducer peptide -
  I6K94_RS09770 (I6K94_09770) - 2089816..2090250 (-) 435 Protein_1918 accessory gene regulator B family protein -
  I6K94_RS09775 (I6K94_09775) dfrG 2090522..2091019 (+) 498 WP_000868795.1 trimethoprim-resistant dihydrofolate reductase DfrG -
  I6K94_RS09780 (I6K94_09780) - 2091091..2093043 (-) 1953 WP_000163792.1 hypothetical protein -
  I6K94_RS09785 (I6K94_09785) - 2093050..2093286 (-) 237 WP_001159903.1 hypothetical protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=537569 I6K94_RS09755 WP_001829999.1 2087623..2088339(-) (agrA) [Staphylococcus epidermidis strain FDAARGOS_1364]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=537569 I6K94_RS09755 WP_001829999.1 2087623..2088339(-) (agrA) [Staphylococcus epidermidis strain FDAARGOS_1364]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAGCTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAAGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATTGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ACTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374