NTDB

Overview

Name	sxy/tfoX	Type	Regulator
Locus tag	JS559_RS09885	Genome accession	NZ_CP069795
Coordinates	2080224..2080880 (-)	Length	218 a.a.
NCBI ID	WP_005609196.1	Uniprot ID	A3N356
Organism	Actinobacillus pleuropneumoniae strain A-85/14
Function	positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2075224..2085880

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JS559_RS09865 (JS559_09870)	nanA	2075598..2076476 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
JS559_RS09870 (JS559_09875)	nagB	2076526..2077329 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
JS559_RS09875 (JS559_09880)	nagA	2077381..2078526 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
JS559_RS09880 (JS559_09885)	fumC	2078675..2080069 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
JS559_RS09885 (JS559_09890)	sxy/tfoX	2080224..2080880 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
JS559_RS09890 (JS559_09895)	rpsJ	2081288..2081599 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
JS559_RS09895 (JS559_09900)	rplC	2081625..2082251 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
JS559_RS09900 (JS559_09905)	rplD	2082267..2082869 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
JS559_RS09905 (JS559_09910)	rplW	2082866..2083171 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
JS559_RS09910 (JS559_09915)	rplB	2083192..2084013 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
JS559_RS09915 (JS559_09920)	rpsS	2084041..2084316 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
JS559_RS09920 (JS559_09925)	rplV	2084327..2084659 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
JS559_RS09925 (JS559_09930)	rpsC	2084678..2085385 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
JS559_RS09930 (JS559_09935)	rplP	2085399..2085809 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

Download Length: 218 a.a. Molecular weight: 25633.15 Da Isoelectric Point: 9.9359

                                >NTDB_id=536676 JS559_RS09885 WP_005609196.1 2080224..2080880(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain A-85/14]

MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS

HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL

IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

Download Length: 657 bp

                                >NTDB_id=536676 JS559_RS09885 WP_005609196.1 2080224..2080880(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain A-85/14]

ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT

TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT

CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT

CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA

ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG

AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG

ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT

ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA

TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

TfoX C-terminal domain (TfoX_C)

(120-196)

TfoX N-terminal domain (TfoX_N)

(13-107)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A3N356

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376

Detailed information NTG0536676