Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LD199_RS07395 Genome accession   NZ_CP084878
Coordinates   1531077..1532855 (-) Length   592 a.a.
NCBI ID   WP_097646264.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GS426     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1526077..1537855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LD199_RS07375 (LD199_07375) racE 1526470..1527270 (-) 801 WP_001039659.1 glutamate racemase -
  LD199_RS07380 (LD199_07380) sdhB 1527506..1528321 (-) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  LD199_RS07385 (LD199_07385) sdhA 1528321..1530087 (-) 1767 WP_226566036.1 succinate dehydrogenase flavoprotein subunit -
  LD199_RS07390 (LD199_07390) - 1530139..1530753 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  LD199_RS07395 (LD199_07395) uvrC 1531077..1532855 (-) 1779 WP_097646264.1 excinuclease ABC subunit UvrC Machinery gene
  LD199_RS07400 (LD199_07400) - 1533021..1533116 (+) 96 WP_001788625.1 hypothetical protein -
  LD199_RS07405 (LD199_07405) trxA 1533179..1533493 (-) 315 WP_001018928.1 thioredoxin -
  LD199_RS07410 (LD199_07410) mutS/mutS2 1533666..1536014 (-) 2349 WP_001249272.1 endonuclease MutS2 Machinery gene
  LD199_RS07415 (LD199_07415) polX 1536024..1537736 (-) 1713 WP_000161938.1 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 592 a.a.        Molecular weight: 68558.30 Da        Isoelectric Point: 9.7857

>NTDB_id=535655 LD199_RS07395 WP_097646264.1 1531077..1532855(-) (uvrC) [Staphylococcus aureus strain GS426]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYCVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQ
SVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSAM
VTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVAG
LQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFG
SIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1779 bp        

>NTDB_id=535655 LD199_RS07395 WP_097646264.1 1531077..1532855(-) (uvrC) [Staphylococcus aureus strain GS426]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGAGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGTTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATAAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATTGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAATTTTATACATTTATTG
GACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATTCAA
TCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGCTAA
AGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCAAGAACGATTAAAGCTATTGAAGAACTTGGAACAC
AAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCAATG
GTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGATTA
CAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAATAG
TCGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCAGGT
TTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAATAG
CCAGGCATTTTATTTGTTGCATCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTCAAA
AGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCATTCGGT
TCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCTACA
TGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(378-525)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.436

98.818

0.568
  uvrC Streptococcus pneumoniae R6

57.436

98.818

0.568
  uvrC Streptococcus pneumoniae D39

57.436

98.818

0.568