Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I6J73_RS06865 Genome accession   NZ_CP069473
Coordinates   1442885..1443601 (-) Length   238 a.a.
NCBI ID   WP_204116003.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain FDAARGOS_1243     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1437885..1448601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J73_RS06850 (I6J73_06850) - 1439166..1440119 (+) 954 WP_002468995.1 LacI family DNA-binding transcriptional regulator -
  I6J73_RS06855 (I6J73_06855) - 1440379..1441851 (+) 1473 WP_002469009.1 sucrose-6-phosphate hydrolase -
  I6J73_RS06860 (I6J73_06860) - 1441858..1442817 (+) 960 WP_002469008.1 carbohydrate kinase -
  I6J73_RS06865 (I6J73_06865) agrA 1442885..1443601 (-) 717 WP_204116003.1 LytTR family DNA-binding domain-containing protein Regulator
  I6J73_RS06870 (I6J73_06870) - 1443618..1444907 (-) 1290 WP_002440376.1 GHKL domain-containing protein -
  I6J73_RS06875 (I6J73_06875) - 1444934..1445074 (-) 141 WP_001830021.1 cyclic lactone autoinducer peptide -
  I6J73_RS06880 (I6J73_06880) - 1445058..1445642 (-) 585 WP_001830005.1 accessory gene regulator B family protein -
  I6J73_RS06885 (I6J73_06885) hld 1445960..1446037 (+) 78 WP_002494082.1 delta-hemolysin -
  I6J73_RS06890 (I6J73_06890) - 1446418..1447203 (-) 786 WP_001830000.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27951.00 Da        Isoelectric Point: 5.6250

>NTDB_id=534941 I6J73_RS06865 WP_204116003.1 1442885..1443601(-) (agrA) [Staphylococcus epidermidis strain FDAARGOS_1243]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESTTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=534941 I6J73_RS06865 WP_204116003.1 1442885..1443601(-) (agrA) [Staphylococcus epidermidis strain FDAARGOS_1243]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCCTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGACATTATG
TTTTTTGAATCAACTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.573

100

0.378
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.573

100

0.378