Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I6G24_RS01690 Genome accession   NZ_CP084189
Coordinates   249534..250901 (+) Length   455 a.a.
NCBI ID   WP_017864854.1    Uniprot ID   -
Organism   Lactococcus lactis strain FDAARGOS_867     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 244534..255901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G24_RS01675 (I6G24_01670) - 245212..247467 (+) 2256 WP_003130366.1 glycoside hydrolase family 65 protein -
  I6G24_RS01680 (I6G24_01675) - 247620..248594 (+) 975 WP_023164411.1 LacI family DNA-binding transcriptional regulator -
  I6G24_RS01685 (I6G24_01680) ciaR 248772..249440 (+) 669 WP_021722129.1 response regulator transcription factor Regulator
  I6G24_RS01690 (I6G24_01685) ciaH 249534..250901 (+) 1368 WP_017864854.1 cell wall metabolism sensor histidine kinase WalK Regulator
  I6G24_RS01695 (I6G24_01690) - 251049..252791 (+) 1743 WP_010906088.1 1-deoxy-D-xylulose-5-phosphate synthase -
  I6G24_RS01700 (I6G24_01695) yidD 252908..253174 (+) 267 WP_010906087.1 membrane protein insertion efficiency factor YidD -
  I6G24_RS01705 (I6G24_01700) - 253297..254731 (+) 1435 Protein_248 6-phospho-beta-glucosidase -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 51200.75 Da        Isoelectric Point: 9.4771

>NTDB_id=534338 I6G24_RS01690 WP_017864854.1 249534..250901(+) (ciaH) [Lactococcus lactis strain FDAARGOS_867]
MKKIIKKIKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLEEAANNQLGTSSSQD
SGFGPNNSVIFYDSEGKNFMPSTGSNANISTNFGMSLLQKAMKFNEKHINTIQTVSVKNPYGDNLHYRYYTTSQFIITNS
DGTVTPVYMQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSIIISLYLANWTLRPILAAYEKQKEFVENASHELRTPLAIL
QNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKFS
GHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKARTR
QKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=534338 I6G24_RS01690 WP_017864854.1 249534..250901(+) (ciaH) [Lactococcus lactis strain FDAARGOS_867]
TTGAAGAAAATAATTAAAAAAATTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTGTTTTTGGAAGAAGCAGCGAATAATCAATTAGGAACAAGTAGTTCACAAGAC
AGTGGCTTTGGACCTAATAATAGTGTAATTTTTTATGATTCAGAAGGAAAAAACTTTATGCCGTCAACGGGCTCAAATGC
AAATATAAGTACAAACTTTGGCATGAGTCTTTTGCAAAAAGCAATGAAATTTAATGAAAAACATATAAATACAATTCAGA
CAGTATCTGTAAAAAATCCTTATGGAGATAATTTGCACTATCGTTATTACACAACATCGCAATTTATCATTACAAATTCT
GATGGTACTGTGACGCCAGTTTATATGCAAATTTTTTCAAACGTTGACCAAATTCAAGATGCCATGAGTCGTGCCATGTG
GGTCATTGTGACAACAATGATTACTTTCTGGCTACTATCAATAATTATTAGTTTGTATCTTGCAAATTGGACATTAAGAC
CTATTCTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATCTTG
CAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACTGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTTATC
TGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGCCAG
AGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTTTCA
GGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTGACCATCTTATTTGATAATGC
TCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCGCCG
ATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACGCGT
CAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGAAGA
TAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCCAAA
AGTTGTAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(222-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-441)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.372

94.505

0.457
  ciaH Streptococcus pneumoniae Rx1

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae D39

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae R6

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae TIGR4

44.444

98.901

0.44