Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   JQ461_RS23615 Genome accession   NZ_CP069324
Coordinates   5070956..5072293 (+) Length   445 a.a.
NCBI ID   WP_124135745.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain R05     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5065956..5077293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JQ461_RS23590 (JQ461_23565) pgeF 5066099..5066827 (-) 729 WP_003102588.1 peptidoglycan editing factor PgeF -
  JQ461_RS23595 (JQ461_23570) rluD 5066824..5067786 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  JQ461_RS23600 (JQ461_23575) - 5067932..5068957 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  JQ461_RS23605 (JQ461_23580) - 5069114..5069359 (+) 246 WP_003102591.1 PP0621 family protein -
  JQ461_RS23610 (JQ461_23585) pilS 5069349..5070941 (+) 1593 WP_003123394.1 two-component system sensor histidine kinase PilS Regulator
  JQ461_RS23615 (JQ461_23590) pilR 5070956..5072293 (+) 1338 WP_124135745.1 two-component system response regulator PilR Regulator
  JQ461_RS23620 (JQ461_23595) thiO 5072339..5073433 (-) 1095 WP_003119424.1 glycine oxidase ThiO -
  JQ461_RS23625 (JQ461_23600) - 5073568..5074077 (+) 510 WP_003102595.1 Tfp pilus assembly protein FimT/FimU -
  JQ461_RS23630 (JQ461_23605) - 5074183..5074689 (+) 507 WP_003102598.1 Tfp pilus assembly protein FimT/FimU -
  JQ461_RS23635 (JQ461_23610) pilV 5074680..5075237 (+) 558 WP_003119423.1 type 4a pilus minor pilin PilV Machinery gene
  JQ461_RS23640 (JQ461_23615) pilW 5075234..5076058 (+) 825 WP_003119422.1 type 4a pilus minor pilin PilW -
  JQ461_RS23645 (JQ461_23620) pilX 5076055..5076642 (+) 588 WP_003112826.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49737.06 Da        Isoelectric Point: 5.8654

>NTDB_id=533590 JQ461_RS23615 WP_124135745.1 5070956..5072293(+) (pilR) [Pseudomonas aeruginosa strain R05]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRINVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=533590 JQ461_RS23615 WP_124135745.1 5070956..5072293(+) (pilR) [Pseudomonas aeruginosa strain R05]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCATCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.775

100

0.998
  pilR Acinetobacter baumannii strain A118

51.416

100

0.53
  luxO Vibrio cholerae strain A1552

37.946

100

0.382