Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JN168_RS04750 Genome accession   NZ_CP069082
Coordinates   1046269..1046898 (+) Length   209 a.a.
NCBI ID   WP_042739175.1    Uniprot ID   A0A0D0SM65
Organism   Staphylococcus gallinarum strain STP534     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1041269..1051898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JN168_RS04725 - 1042117..1043103 (-) 987 WP_229366878.1 aromatic acid exporter family protein -
  JN168_RS04730 map 1043278..1044030 (+) 753 WP_042739179.1 type I methionyl aminopeptidase -
  JN168_RS04735 - 1044135..1044521 (+) 387 WP_042739178.1 hypothetical protein -
  JN168_RS04740 liaF 1044538..1045239 (+) 702 WP_042739177.1 cell wall-active antibiotics response protein LiaF -
  JN168_RS04745 vraS 1045236..1046279 (+) 1044 WP_042739176.1 sensor histidine kinase Regulator
  JN168_RS04750 vraR 1046269..1046898 (+) 630 WP_042739175.1 response regulator transcription factor Regulator
  JN168_RS04755 - 1046951..1048024 (-) 1074 WP_042739174.1 YihY/virulence factor BrkB family protein -
  JN168_RS04760 - 1048228..1048512 (-) 285 WP_042739173.1 hypothetical protein -
  JN168_RS04765 - 1048519..1048983 (-) 465 WP_042739172.1 low molecular weight protein-tyrosine-phosphatase -
  JN168_RS04770 - 1049138..1049320 (+) 183 WP_082039199.1 DUF1128 family protein -
  JN168_RS04775 - 1049339..1050574 (+) 1236 WP_229366879.1 aminopeptidase -
  JN168_RS04780 - 1050696..1051217 (+) 522 WP_042739169.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23590.07 Da        Isoelectric Point: 4.7039

>NTDB_id=532235 JN168_RS04750 WP_042739175.1 1046269..1046898(+) (vraR) [Staphylococcus gallinarum strain STP534]
MTIKVLFVDDHEMVRIGISSYLSTQSDIDVVGEGKSGKEAIEKAHELQPDLILMDLLMDDMDGVEATEQVKKDLPQIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTHAGESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=532235 JN168_RS04750 WP_042739175.1 1046269..1046898(+) (vraR) [Staphylococcus gallinarum strain STP534]
ATGACGATTAAAGTATTATTTGTTGATGATCATGAAATGGTTAGAATAGGAATTTCAAGTTATTTATCAACACAGTCAGA
TATTGATGTGGTAGGAGAAGGTAAATCAGGAAAAGAAGCTATTGAAAAGGCACATGAACTACAACCAGATTTAATCTTGA
TGGATTTACTCATGGATGACATGGACGGTGTCGAAGCTACCGAGCAAGTTAAAAAGGACTTACCTCAAATCAAAGTAGTT
ATGTTAACAAGTTATATAGAAGATAACGAAGTATATCGAGCACTAGATTCAGGGGTTGATAGTTATATTCTAAAGACAAC
AAGTGCAAGTGATATTGCTGAAGCAATTAGGAAAACACATGCTGGTGAATCTGTTTTTGAAGCAGAAGTACTAGTGAAAA
TGCGTAATAGAATGAAACAACGTGCAGAATTATATGAAATGTTAACAGAGCGTGAAATGGAAATCTTATTACTTATAGCT
AAAGGTTATTCAAATCAAGAAATCGCGAGCGCATCACATATAACAATTAAGACCGTTAAGACACATGTTAGTAATATATT
GAGTAAACTTGAAGTTCAAGATAGAACACAGGCTGTTATCTATGCCTTTCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D0SM65

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

91.388

100

0.914
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368