Detailed information NTG0532234

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JN168_RS04745
• Genome accession: NZ_CP069082
• Coordinates: 1045236..1046279 (+)
• Length: 347 a.a.
• NCBI ID: WP_042739176.1
• Uniprot ID: A0A0D0SQ17
• Organism: Staphylococcus gallinarum strain STP534
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1040236..1051279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JN168_RS04720	-	1041101..1041817 (+)	717	WP_042739181.1	type 1 glutamine amidotransferase	-
JN168_RS04725	-	1042117..1043103 (-)	987	WP_229366878.1	aromatic acid exporter family protein	-
JN168_RS04730	map	1043278..1044030 (+)	753	WP_042739179.1	type I methionyl aminopeptidase	-
JN168_RS04735	-	1044135..1044521 (+)	387	WP_042739178.1	hypothetical protein	-
JN168_RS04740	liaF	1044538..1045239 (+)	702	WP_042739177.1	cell wall-active antibiotics response protein LiaF	-
JN168_RS04745	vraS	1045236..1046279 (+)	1044	WP_042739176.1	sensor histidine kinase	Regulator
JN168_RS04750	vraR	1046269..1046898 (+)	630	WP_042739175.1	response regulator transcription factor	Regulator
JN168_RS04755	-	1046951..1048024 (-)	1074	WP_042739174.1	YihY/virulence factor BrkB family protein	-
JN168_RS04760	-	1048228..1048512 (-)	285	WP_042739173.1	hypothetical protein	-
JN168_RS04765	-	1048519..1048983 (-)	465	WP_042739172.1	low molecular weight protein-tyrosine-phosphatase	-
JN168_RS04770	-	1049138..1049320 (+)	183	WP_082039199.1	DUF1128 family protein	-
JN168_RS04775	-	1049339..1050574 (+)	1236	WP_229366879.1	aminopeptidase	-
JN168_RS04780	-	1050696..1051217 (+)	522	WP_042739169.1	acyl-CoA thioesterase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40025.44 Da
• Isoelectric Point: 6.0579

>NTDB_id=532234 JN168_RS04745 WP_042739176.1 1045236..1046279(+) (vraS) [Staphylococcus gallinarum strain STP534]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLLVILLCIIVGSVLAYKINQQNHWLQN
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESNLEPPLNQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNKEDYLLLRIQDDGKGFNVDDKLEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEESNDD

Nucleotide

• Length: 1044 bp

>NTDB_id=532234 JN168_RS04745 WP_042739176.1 1045236..1046279(+) (vraS) [Staphylococcus gallinarum strain STP534]
GTGAATCACTATATAAGAGCGATTGGCTCGATGTTAATATTAGTTTATAGTACATTTTTTGCAATCTTTTTTATAGATAA
AGTGTTTGTAAATATCATGTATTTCCAGGGCATGTTTTACACACAAATATTTGGTATTCCAGTATTACTTTTTCTAAATT
TACTAGTAATATTGTTATGTATCATTGTGGGTTCTGTTTTAGCTTATAAAATAAATCAACAAAATCATTGGTTACAAAAC
CAAATAGAACGCTCAATTGAAGGTCAAACAGTAGGGATTAATGACCAAAATATTGAACTGTACAATGAAACGATAGAATT
GTACCAAACGTTAGTGCCACTTAATCAAGAGGTACATAAACTGCGTATGAAGACGCAAAATTTAACAAATGAGTCATACA
ATATTAATGACGTTAAGGTTAAAAAAATAATAGAAGATGAAAGACAAAGGTTAGCTAGAGAATTACATGATTCTGTAAGT
CAGCAATTGTTCGCTGCGAGTATGATGCTTTCAGCTATTAAAGAATCGAACTTGGAGCCACCTTTAAACCAACAAATTCC
AGTCCTAGAAAAAATGATTCAAGATTCACAACTAGAAATGCGTGCTTTACTCTTACATTTGAGACCAATTGGTTTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCGTTGATTTACAAAAGAAAGTACCTATGAAGGTTGTACATGATATT
GAAGAATTTAAAGTACCTAAAGGTATCGAGGATCATTTGTTTAGAATAACGCAAGAAGCTATTTCTAATACATTAAGACA
TTCTAAGGGAACTAAAGTTACGATTGAATTATTTAATAAAGAAGATTATCTTTTATTACGTATTCAAGATGATGGGAAAG
GCTTTAATGTTGACGATAAATTAGAGCAAAGTTATGGGTTGAAAAATATGCGAGAACGTGCACTTGAAATTGGCGCGACT
TTCCATATTGTATCGTTACCTGATGCAGGTACAAGAATTGAAGTGAAAGCACCGTTAAATAAGGAGGAGTCTAATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A0D0SQ17

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.896	100	0.879