Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   K8Z53_RS22405 Genome accession   NZ_CP083238
Coordinates   4212613..4213911 (+) Length   432 a.a.
NCBI ID   WP_061576239.1    Uniprot ID   -
Organism   Bacillus licheniformis strain 2709     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4207613..4218911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8Z53_RS22380 (K8Z53_22095) - 4207654..4208685 (-) 1032 WP_142782630.1 ABC transporter ATP-binding protein -
  K8Z53_RS22385 (K8Z53_22100) - 4208693..4209652 (-) 960 WP_009328700.1 ABC transporter permease -
  K8Z53_RS22390 (K8Z53_22105) - 4209657..4210583 (-) 927 WP_009328701.1 ABC transporter permease -
  K8Z53_RS22395 (K8Z53_22110) - 4210599..4211423 (-) 825 WP_009328702.1 M55 family metallopeptidase -
  K8Z53_RS22400 (K8Z53_22115) proG 4211642..4212454 (-) 813 WP_061576240.1 pyrroline-5-carboxylate reductase ProG -
  K8Z53_RS22405 (K8Z53_22120) htrA 4212613..4213911 (+) 1299 WP_061576239.1 S1C family serine protease Regulator
  K8Z53_RS22410 (K8Z53_22125) - 4214085..4214447 (-) 363 WP_003180937.1 hypothetical protein -
  K8Z53_RS22415 (K8Z53_22130) - 4214841..4215794 (-) 954 WP_011197826.1 ring-cleaving dioxygenase -
  K8Z53_RS22420 (K8Z53_22135) - 4216114..4217442 (+) 1329 WP_009328706.1 APC family permease -
  K8Z53_RS22425 (K8Z53_22140) - 4217480..4218364 (-) 885 WP_003180929.1 carbohydrate ABC transporter permease -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 45561.75 Da        Isoelectric Point: 4.7106

>NTDB_id=531272 K8Z53_RS22405 WP_061576239.1 4212613..4213911(+) (htrA) [Bacillus licheniformis strain 2709]
MEYNREDQLETKNELIVSDQKPDQAIKKAEQQKRRLSWMTPILSGIIGGSLVLGVTTYQHSIDETANTSVQTQTNETSNS
SASSTKANTEKLSSTNSSDISTMVENVSPAIVGISNYQKQTESGMFGFESNSSSSSEQETGTGSGVIYKKANGKAYIITN
NHVVEGASKLTVSLSNGKEVEGKLLGSDSLTDLAVVEISADHVEKVASFGDSSSLKAGESVIAIGNPLGKDLSRTVTQGI
ISGVDRTVSVDTSAGQTEMNVIQTDAAINPGNSGGALLNTKGEVIGINSMKISESGVEGIGFAIPSNDVKPIAEELMSKG
KIERPFIGIGMMDLEQVPENYQTGTLGLSGSQLNKGVYIRQVASGSPAEKAGLKENDVIVSFNGKETDTGSALRNLLYND
AKIGDTVKVTLIRNGKTMTKQITLDQKESASS

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=531272 K8Z53_RS22405 WP_061576239.1 4212613..4213911(+) (htrA) [Bacillus licheniformis strain 2709]
ATGGAATATAATAGAGAAGATCAGCTTGAAACAAAAAACGAACTCATCGTCTCCGATCAAAAGCCCGACCAGGCGATAAA
AAAAGCAGAACAGCAAAAGCGGAGACTCTCGTGGATGACGCCGATTCTCAGCGGCATCATCGGAGGAAGCCTCGTTCTCG
GCGTCACGACATACCAGCATAGCATAGACGAAACGGCCAATACATCCGTCCAGACGCAAACAAACGAGACGTCGAACTCA
TCGGCTTCTTCCACTAAAGCGAATACCGAAAAATTGTCCAGCACCAATTCGTCCGACATTTCTACAATGGTTGAAAATGT
ATCTCCCGCCATCGTCGGTATTTCAAACTATCAAAAACAAACAGAGAGCGGTATGTTCGGTTTTGAAAGCAACAGCAGCA
GCTCAAGCGAACAAGAAACAGGCACAGGCTCAGGTGTCATCTATAAAAAAGCAAACGGCAAAGCATATATTATTACAAAT
AACCACGTTGTCGAAGGCGCGTCTAAACTGACGGTTTCCCTGTCCAACGGCAAAGAAGTGGAAGGTAAATTGCTGGGCAG
CGATTCGTTGACAGACCTTGCCGTTGTTGAAATTTCCGCTGATCACGTGGAAAAAGTCGCCTCTTTCGGCGATTCGTCAA
GCTTGAAAGCAGGCGAATCGGTGATCGCTATTGGAAACCCGCTCGGCAAAGATCTGTCCCGCACGGTGACACAAGGCATC
ATCAGCGGTGTTGATCGGACCGTTTCCGTAGATACATCCGCAGGCCAAACCGAGATGAACGTCATTCAAACCGACGCGGC
CATCAACCCCGGCAACAGCGGAGGCGCCCTTTTGAATACAAAGGGTGAAGTGATCGGCATCAACAGCATGAAAATCAGTG
AAAGCGGAGTAGAAGGCATCGGATTTGCGATTCCAAGCAATGATGTCAAACCGATTGCAGAAGAGCTGATGTCTAAAGGA
AAAATTGAGCGCCCGTTCATCGGAATCGGAATGATGGATCTTGAGCAGGTGCCGGAAAACTATCAAACAGGCACGCTCGG
ATTAAGCGGCAGCCAGTTAAACAAAGGCGTCTACATCCGCCAGGTCGCTTCAGGCTCCCCAGCTGAAAAAGCGGGCCTTA
AAGAGAACGATGTCATCGTCAGCTTTAACGGAAAAGAAACCGATACAGGAAGCGCGCTGCGCAACCTTCTTTACAACGAT
GCAAAAATCGGGGATACGGTAAAGGTTACCCTCATTCGAAACGGCAAAACCATGACAAAACAAATCACCCTTGACCAGAA
AGAATCCGCATCATCTTAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(261-429)

PDZ domain (PDZ_2)

(327-424)

Trypsin-like peptidase domain (Trypsin_2)

(143-287)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

42.04

93.056

0.391
  htrA Streptococcus gordonii str. Challis substr. CH1

38.971

94.444

0.368
  htrA Streptococcus mitis NCTC 12261

43.733

83.102

0.363