Detailed information NTG0530930

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: K8227_RS05025
• Genome accession: NZ_CP082948
• Coordinates: 1027570..1029555 (-)
• Length: 661 a.a.
• NCBI ID: WP_012028187.1
• Uniprot ID: A0A0H3N3Z6
• Organism: Streptococcus suis strain SZ1908
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1022570..1034555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8227_RS10560 (K8227_05015)	-	1025591..1025689 (-)	99	Protein_943	UvrB/UvrC motif-containing protein	-
K8227_RS05020 (K8227_05020)	-	1025732..1027555 (-)	1824	WP_014636397.1	DUF2971 domain-containing protein	-
K8227_RS05025 (K8227_05025)	uvrB	1027570..1029555 (-)	1986	WP_012028187.1	excinuclease ABC subunit UvrB	Machinery gene
K8227_RS05030 (K8227_05030)	-	1029753..1031951 (+)	2199	WP_012775143.1	ABC transporter substrate-binding protein/permease	-
K8227_RS05035 (K8227_05035)	-	1031951..1032691 (+)	741	WP_002940438.1	amino acid ABC transporter ATP-binding protein	-
K8227_RS05040 (K8227_05040)	-	1032945..1033436 (-)	492	WP_011922516.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 661 a.a.
• Molecular weight: 75592.64 Da
• Isoelectric Point: 4.5993

>NTDB_id=530930 K8227_RS05025 WP_012028187.1 1027570..1029555(-) (uvrB) [Streptococcus suis strain SZ1908]
MINRNTENQFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILMGATGTGKTYTMSQVIARVNKPTLVIAHNKTLAGQLYS
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREIESLTGKVL
GDVDHLAIFPATHFVTNDDHMETAIAKIQAELEEQLKVFEAEGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPEDYLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTETVVEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINARVEKGERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADK
VTESMRKAMEETARRRQIQMAYNEEHGIIPQTIKKEIRDLISVTKAVTQDKEEVVDFNALNKDERKAMIKKLEGQMQEAA
EVLDFELAAQIRDMVIELKNM

Nucleotide

• Length: 1986 bp

>NTDB_id=530930 K8227_RS05025 WP_012028187.1 1027570..1029555(-) (uvrB) [Streptococcus suis strain SZ1908]
ATGATCAATCGAAATACTGAAAACCAATTTAAACTTGTGTCAAAATATGCACCGTCTGGTGACCAGCCCCAAGCCATTGA
AACCTTGGTTGATAACATCGAGGGGGGCGAAAAAGCCCAGATTCTCATGGGGGCGACTGGTACTGGTAAGACCTATACCA
TGAGCCAGGTTATCGCCCGTGTCAATAAGCCAACCTTGGTCATCGCCCACAACAAGACCTTGGCTGGTCAGCTTTATAGT
GAGTTCAAGGAATTCTTTCCAGAAAATGCGGTCGAATACTTCGTGTCTTACTATGATTACTACCAGCCAGAAGCTTATGT
ACCGTCTAGCGATACCTATATCGAAAAGGATAGTTCGGTCAATGATGAGATTGACAAACTCCGTCACTCTGCGACCTCAG
CTCTGCTAGAACGCAATGATGTCATTGTGGTAGCTTCTGTTTCTTGTATCTACGGTTTGGGTTCACCCAAGGAATATTCA
GATAGCGTGGTCAGCCTGCGACCAGGTCAGGAGATTTCCCGTGATCAGTTGCTCAATGCCTTGGTGGATATCCAGTTTGA
GCGGAACGACATCGACTTCCAACGGGGACGGTTCCGTGTGCGTGGCGATGTGGTGGAGATTTTCCCAGCTTCCCGTGACG
AACATGCCTTTCGTGTGGAGTTTTTCGGGGATGAAATCGACCGCATTCGTGAGATTGAAAGCCTGACAGGCAAGGTTTTG
GGCGATGTGGACCACTTGGCCATTTTCCCTGCCACCCACTTCGTGACCAACGATGACCACATGGAAACGGCCATTGCCAA
GATTCAGGCGGAACTAGAAGAGCAACTCAAGGTCTTTGAGGCAGAAGGAAAACTCTTAGAAGCTCAGCGATTGAAACAAC
GAACCGACTACGATATCGAGATGCTTCGGGAGATGGGCTATACCAACGGAGTTGAGAACTATTCACGACACATGGACGGG
CGAAGTGAGGGGGAGCCTCCTTATACCCTGCTGGACTTTTTCCCTGAGGACTATCTGATTATGATTGACGAGAGCCACAT
GACCATGGGGCAGATTAAGGGGATGTACAATGGTGACCGCTCACGCAAGGAGATGCTGGTTAACTATGGTTTCCGTCTAC
CGAGTGCATTGGATAATCGTCCGCTGCGCAGGGAAGAATTTGAGAGTCATGTCCACCAGATTGTCTATGTATCTGCGACG
CCGGGTGACTATGAAATGGAGCAGACAGAGACCGTTGTCGAGCAGATTATCCGGCCGACCGGGCTTTTGGATCCAGAAGT
GGAAGTCCGTCCAACTATGGGCCAAATGGACGACCTCCTAGGTGAAATCAATGCCCGTGTTGAAAAAGGCGAGCGAACCT
TTATCACTACCCTGACCAAGAAAATGGCAGAGGACTTGACCGACTACCTGAAAGAAATGGGCGTCAAGGTCAAGTATATG
CACTCGGACATCAAGACCTTGGAGCGTACGGAGATTATCCGTGATCTTCGCTTGGGTGTCTTTGATGTTTTGATAGGGAT
TAACCTGCTTCGTGAAGGGATTGACGTGCCAGAAGTTAGTCTAGTCGCTATCTTAGACGCAGACAAGGAGGGCTTCCTCC
GTAATGAACGGGGGCTCATCCAGACAATCGGTCGAGCGGCTCGTAACTCTGAAGGTCATGTGATTATGTATGCGGACAAG
GTCACCGAGTCCATGCGGAAGGCCATGGAAGAAACAGCCCGCCGCCGTCAAATCCAGATGGCTTATAATGAAGAGCATGG
CATTATTCCACAGACCATTAAGAAAGAGATCCGTGACCTGATTAGCGTGACCAAGGCTGTCACTCAGGACAAGGAAGAGG
TTGTGGACTTCAATGCTCTTAATAAAGATGAACGCAAGGCCATGATCAAGAAACTGGAAGGTCAGATGCAGGAAGCCGCA
GAAGTGCTTGACTTTGAACTGGCAGCCCAGATTCGCGATATGGTCATTGAGTTGAAGAATATGTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• Type III restriction enzyme, res subunit (ResIII) (21-143)

• UvrB/uvrC motif (UVR) (626-660)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (445-549)

3D structure

• AlphaFold DB: A0A0H3N3Z6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	91.225	100	0.912
uvrB	Streptococcus pneumoniae D39	91.225	100	0.912
uvrB	Streptococcus pneumoniae TIGR4	91.074	100	0.911