Detailed information NTG0530624

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: JM955_RS00525
• Genome accession: NZ_CP068717
• Coordinates: 94907..97342 (+)
• Length: 811 a.a.
• NCBI ID: WP_000971170.1
• Uniprot ID: A0A9W7V441
• Organism: Bacillus cereus strain CH
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 89907..102342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JM955_RS00510	ctsR	92635..93096 (+)	462	WP_001244560.1	transcriptional regulator CtsR	-
JM955_RS00515	-	93267..93815 (+)	549	WP_000128385.1	UvrB/UvrC motif-containing protein	-
JM955_RS00520	-	93820..94884 (+)	1065	WP_000050836.1	protein arginine kinase	-
JM955_RS00525	clpC	94907..97342 (+)	2436	WP_000971170.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
JM955_RS00530	radA	97438..98814 (+)	1377	WP_001085199.1	DNA repair protein RadA	Machinery gene
JM955_RS00535	disA	98818..99891 (+)	1074	WP_063546189.1	DNA integrity scanning diadenylate cyclase DisA	-
JM955_RS00540	-	100052..101155 (+)	1104	WP_000919679.1	PIN/TRAM domain-containing protein	-
JM955_RS00545	ispD	101172..101852 (+)	681	WP_000288307.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 811 a.a.
• Molecular weight: 90540.42 Da
• Isoelectric Point: 6.4057

>NTDB_id=530624 JM955_RS00525 WP_000971170.1 94907..97342(+) (clpC) [Bacillus cereus strain CH]
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSASNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLEESIQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRLIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

Nucleotide

• Length: 2436 bp

>NTDB_id=530624 JM955_RS00525 WP_000971170.1 94907..97342(+) (clpC) [Bacillus cereus strain CH]
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCAATTCGTATTGGGCATAA
TAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCATTAATTGCTCTTG
GATTAAGTCCAGAGAAAGTTCAAAAAGAAGTAGAAGCGTTAATTGGGCGTGGAACAGAAGCTTCTCAAACTGTACATTAT
ACACCTCGTGCTAAAAAGGTTATTGAATTATCTATGGATGAAGCGCGTAAGCTAGGCCATTCTTACGTTGGAACAGAACA
CATTTTACTCGGTTTAATCCGTGAAGGTGAAGGTGTAGCCGCACGTGTTTTAAATAATTTAGGTGTAAGTCTAAATAAAG
CAAGACAACAAGTTTTACAACTTCTTGGAAGTAATGAAGCTAGTTCAGGTCATCAAGGTGGTTCAGCATCAAATGCAAAT
ACACCGACACTTGACAGTTTAGCAAGGGACTTAACAGTTGTTGCGCGTGAAAATCGCTTAGACCCTGTTATTGGACGTGG
TAAAGAAATTCAACGTGTAATTGAGGTATTAAGCCGTAGAACGAAAAACAACCCAGTATTAATTGGTGAGCCTGGTGTAG
GTAAAACGGCAATTGCAGAAGGATTAGCACAGCAAATTGTAAATAATGAAGTTCCTGAAACTTTAAGAGATAAGCGTGTT
ATGACACTAGATATGGGTACAGTGGTAGCTGGAACGAAATATCGCGGTGAATTTGAAGATCGTTTAAAGAAAGTGATGGA
TGAAATTCGCCAAGCAGGCAATATTATTCTATTTATTGATGAGCTTCATACATTAATTGGTGCAGGTGGAGCAGAAGGTG
CAATCGATGCATCGAATATTTTAAAACCATCTTTAGCACGAGGAGAGTTACAATGTATTGGGGCAACAACTTTAGATGAG
TATCGTAAATATATTGAAAAAGACGCGGCTTTAGAAAGACGTTTTCAACCAATTCATGTTGATGAGCCAAGTTTAGAAGA
ATCGATTCAAATCTTGAAAGGTTTACGTGATCGTTATGAGGCGCATCACCGTGTATCTATTACAGATGACGCTATTGATG
CAGCTGTAAAACTTTCAGATCGTTATATTACAGATCGCTTTTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAAGTTCGCTTACGTTCTTATACAACACCACCAAACTTAAAAGAGCTTGAAGTGAAGCTTGAGGAGATTCGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAATTTGAAAAGGCTGCATCCTTACGTGATATGGAGCAACGCTTACGTGAGAAGT
TAGAAGATACAAAACGTCAATGGAAAGAGCAACAAGGAAAAGAAAATTCAGAGGTTACGGTAGAAGATATTGCAAATGTC
GTTTCTACATGGACGCGTATCCCAGTTTCTAAACTTGCACAAACAGAGACTGATAAATTATTAAATTTAGAATCCATTCT
CCATGATCGTTTGATTGGTCAAGATGAAGCAGTAGTAGCTGTAGCAAAAGCTGTTCGTCGTGCAAGAGCAGGATTAAAAG
ATCCGAAGCGCCCAATTGGTTCATTTATTTTCTTAGGGCCAACAGGTGTAGGTAAAACAGAACTTGCAAGAGCACTAGCA
GAATCTATGTTCGGTGATGAAGATGCAATGATTCGCATCGATATGTCAGAATACATGGAGAAGCATTCTACTTCCCGTTT
AGTTGGTTCTCCTCCAGGATATGTTGGATATGAAGAAGGTGGACAATTAACAGAGAAAGTTCGTCGCAAGCCATATTCAG
TTGTCTTATTAGATGAGGTAGAGAAAGCTCATCCGGATGTGTTTAATATTTTACTACAAGTATTAGAAGATGGTCGTTTA
ACAGATTCTAAAGGACGTACAGTTGATTTCCGTAATACGATTGTTATTATGACGTCTAACGTTGGTGCCGAGGCGTTAAA
ACGTAACAAACATCTTGGATTTAATGTACAAGATGAAAGCCGTGATTATTCGGATATGAAAGGTAAAGTAATGGATGAGC
TGAAAAAGGCATTTCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTATTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACTCTTATGGTAAATCAGTTAGTTAATCGCTTAAAAGAACAAGAAATCGAATTGCACTTAACGGAAGG
GGCAATTTCAGCTATTGCAGATAAAGGATTTGATCGTGAGTATGGCGCTCGTCCACTTCGCAGAGCAATTCAGAAACATG
TAGAAGATAGACTATCAGAAGAACTTTTAAAAGGTGCTATTGAGAAAGGACAAAAAGTTATCTTTGATGTAGAAGGAGAA
TCATTTGTCATTCATAGTGCGGAAAAGGTAAAATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-143)

• AAA domain (Cdc48 subfamily) (AAA_2) (537-709)

• AAA lid domain (AAA_lid_9) (344-446)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-318)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (715-793)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	85.926	99.877	0.858
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.5	98.644	0.498
clpC	Streptococcus thermophilus LMD-9	46.209	100	0.473
clpC	Streptococcus thermophilus LMG 18311	45.718	100	0.467
clpC	Streptococcus mutans UA159	44.762	100	0.464
clpC	Streptococcus pneumoniae D39	46.55	98.274	0.457
clpC	Streptococcus pneumoniae Rx1	46.55	98.274	0.457
clpC	Streptococcus pneumoniae TIGR4	46.25	98.644	0.456
clpE	Streptococcus mutans UA159	53.191	81.134	0.432
clpE	Streptococcus pneumoniae R6	52.55	79.778	0.419
clpE	Streptococcus pneumoniae TIGR4	52.55	79.778	0.419
clpE	Streptococcus pneumoniae Rx1	52.55	79.778	0.419
clpE	Streptococcus pneumoniae D39	52.55	79.778	0.419
clpC	Lactococcus lactis subsp. cremoris KW2	48.98	84.587	0.414