Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   JMW46_RS13120 Genome accession   NZ_CP068553
Coordinates   2877494..2878207 (+) Length   237 a.a.
NCBI ID   WP_003423570.1    Uniprot ID   -
Organism   Clostridioides difficile strain 2016     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2872494..2883207
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMW46_RS13090 (JMW46_13090) cdd1 2873322..2873567 (+) 246 WP_003418186.1 protein Cdd1 -
  JMW46_RS13095 (JMW46_13095) - 2873760..2874029 (-) 270 WP_003418188.1 DUF3795 domain-containing protein -
  JMW46_RS13100 (JMW46_13100) - 2874202..2874426 (-) 225 WP_003418190.1 hypothetical protein -
  JMW46_RS13105 (JMW46_13105) - 2874906..2875643 (-) 738 WP_003418192.1 ABC transporter permease -
  JMW46_RS13110 (JMW46_13110) - 2875655..2876416 (-) 762 WP_003418193.1 ABC transporter permease -
  JMW46_RS13115 (JMW46_13115) - 2876416..2877339 (-) 924 WP_003418194.1 ABC transporter ATP-binding protein -
  JMW46_RS13120 (JMW46_13120) scnR 2877494..2878207 (+) 714 WP_003423570.1 response regulator transcription factor Regulator
  JMW46_RS13125 (JMW46_13125) - 2878252..2879658 (+) 1407 WP_003418198.1 sensor histidine kinase -
  JMW46_RS13130 (JMW46_13130) - 2880741..2881130 (+) 390 WP_003418199.1 BlaI/MecI/CopY family transcriptional regulator -
  JMW46_RS13135 (JMW46_13135) - 2881624..2882094 (+) 471 WP_003418201.1 VOC family protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 26985.59 Da        Isoelectric Point: 5.8420

>NTDB_id=529291 JMW46_RS13120 WP_003423570.1 2877494..2878207(+) (scnR) [Clostridioides difficile strain 2016]
MIVESIKDKKILVVDDHKELLKMIDEILRKEGFSRIFLASSCEEAVRVFRNIKPDCAILDVVLPDGDGFSIMRKIRETSK
MPVIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVSILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQE
ISLTAKEHSLLLKLYENKGRIVTSDSLCQAIWGDDMYGYENTLMVHIRRVREKIERTPSTPKYLLTVRGLGYKLMIN

Nucleotide


Download         Length: 714 bp        

>NTDB_id=529291 JMW46_RS13120 WP_003423570.1 2877494..2878207(+) (scnR) [Clostridioides difficile strain 2016]
ATGATTGTGGAGTCAATAAAAGATAAAAAAATACTTGTGGTTGATGACCACAAGGAATTATTAAAAATGATAGATGAAAT
CCTAAGAAAAGAGGGATTTAGTAGAATATTTTTAGCATCAAGTTGTGAAGAAGCTGTTAGGGTATTTAGAAATATAAAGC
CAGATTGTGCAATTTTAGATGTTGTATTGCCAGATGGAGATGGTTTCTCTATTATGAGAAAAATTAGAGAGACATCTAAA
ATGCCAGTTATTTTTCTTTCTGCAAGAGGCGAAGATGAGGATAGATTGATTGGTTTGGGCTTAGGAGCTGATGATTATAT
AGTAAAGCCATTTTTACCAAAGGAACTTACTTTAAGACTTGTGAGCATATTAAATCGTGTATATGTGCCTATAGAAGAAG
AAGAGTTACCAGTATTTAAACTGGGAGATTCTGTTGTTGTAAATTTAAATAGTGCATGTGTTGAGAAAGATGGGCAAGAG
ATTTCTCTAACAGCTAAAGAGCATTCACTGCTTTTAAAGTTGTATGAAAATAAAGGTAGAATTGTTACGAGTGATTCACT
ATGTCAAGCTATTTGGGGGGATGATATGTATGGATATGAAAATACCCTTATGGTTCATATTAGAAGGGTTAGAGAGAAGA
TAGAAAGAACTCCATCTACACCTAAATATCTTCTTACAGTAAGAGGTCTTGGATATAAGTTGATGATTAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(11-119)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(158-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

49.784

97.468

0.485
  micA Streptococcus pneumoniae Cp1015

40

99.156

0.397
  vicR Streptococcus mutans UA159

39.224

97.89

0.384