Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   K8B91_RS08245 Genome accession   NZ_CP082777
Coordinates   1724927..1726948 (+) Length   673 a.a.
NCBI ID   WP_000042538.1    Uniprot ID   -
Organism   Escherichia coli O25:H1 strain CU39ES-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1719927..1731948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8B91_RS08225 (K8B91_08190) bioB 1720745..1721785 (+) 1041 WP_000951218.1 biotin synthase BioB -
  K8B91_RS08230 (K8B91_08195) bioF 1721782..1722936 (+) 1155 WP_000638120.1 8-amino-7-oxononanoate synthase -
  K8B91_RS08235 (K8B91_08200) bioC 1722923..1723678 (+) 756 WP_000246763.1 malonyl-ACP O-methyltransferase BioC -
  K8B91_RS08240 (K8B91_08205) bioD 1723671..1724348 (+) 678 WP_000030923.1 dethiobiotin synthase -
  K8B91_RS08245 (K8B91_08210) uvrB 1724927..1726948 (+) 2022 WP_000042538.1 excinuclease ABC subunit UvrB Machinery gene
  K8B91_RS08250 (K8B91_08215) yvcK 1726986..1727894 (-) 909 WP_001304790.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  K8B91_RS08255 (K8B91_08220) moaA 1728291..1729280 (+) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  K8B91_RS08260 (K8B91_08225) moaB 1729302..1729814 (+) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  K8B91_RS08265 (K8B91_08230) moaC 1729817..1730302 (+) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  K8B91_RS08270 (K8B91_08235) moaD 1730295..1730540 (+) 246 WP_000611261.1 molybdopterin synthase sulfur carrier subunit -
  K8B91_RS08275 (K8B91_08240) moaE 1730542..1730994 (+) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  K8B91_RS08280 (K8B91_08245) ybhL 1731131..1731835 (+) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76244.09 Da        Isoelectric Point: 4.8843

>NTDB_id=529029 K8B91_RS08245 WP_000042538.1 1724927..1726948(+) (uvrB) [Escherichia coli O25:H1 strain CU39ES-1]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLMEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=529029 K8B91_RS08245 WP_000042538.1 1724927..1726948(+) (uvrB) [Escherichia coli O25:H1 strain CU39ES-1]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCGGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAATTC
TTTCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAGGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATATGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGTGTTCGTGGCGAGGTGATTGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAGGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCACGCGAGCGCATCGTCCAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGTAAAGTGCTATTGGAAAACAACAAACTGATGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTAGGCTACTGTTCGGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCTGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGTGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTCGACCCGATTATCGAAGTGCGGCC
AGTGGCAACACAGGTGGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTCACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAAGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAACCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTACAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGTTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(552-593)

UvrB/uvrC motif (UVR)

(634-667)

UvrB interaction domain (UvrB_inter)

(159-249)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae R6

56.072

99.108

0.556
  uvrB Streptococcus pneumoniae D39

56.072

99.108

0.556