Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   K8B88_RS08060 Genome accession   NZ_CP082774
Coordinates   1685386..1687407 (+) Length   673 a.a.
NCBI ID   WP_000042533.1    Uniprot ID   Q324B3
Organism   Escherichia coli O16:H6 strain CU37RT-2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1680386..1692407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8B88_RS08040 (K8B88_08015) bioB 1681204..1682244 (+) 1041 WP_000951218.1 biotin synthase BioB -
  K8B88_RS08045 (K8B88_08020) bioF 1682241..1683395 (+) 1155 WP_021523833.1 8-amino-7-oxononanoate synthase -
  K8B88_RS08050 (K8B88_08025) bioC 1683382..1684137 (+) 756 WP_000246763.1 malonyl-ACP O-methyltransferase BioC -
  K8B88_RS08055 (K8B88_08030) bioD 1684130..1684807 (+) 678 WP_021523834.1 dethiobiotin synthase -
  K8B88_RS08060 (K8B88_08035) uvrB 1685386..1687407 (+) 2022 WP_000042533.1 excinuclease ABC subunit UvrB Machinery gene
  K8B88_RS08065 (K8B88_08040) yvcK 1687445..1688353 (-) 909 WP_001304790.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  K8B88_RS08070 (K8B88_08045) moaA 1688750..1689739 (+) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  K8B88_RS08075 (K8B88_08050) moaB 1689761..1690273 (+) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  K8B88_RS08080 (K8B88_08055) moaC 1690276..1690761 (+) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  K8B88_RS08085 (K8B88_08060) moaD 1690754..1690999 (+) 246 WP_000611261.1 molybdopterin synthase sulfur carrier subunit -
  K8B88_RS08090 (K8B88_08065) moaE 1691001..1691453 (+) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  K8B88_RS08095 (K8B88_08070) ybhL 1691590..1692294 (+) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76226.06 Da        Isoelectric Point: 4.8843

>NTDB_id=528772 K8B88_RS08060 WP_000042533.1 1685386..1687407(+) (uvrB) [Escherichia coli O16:H6 strain CU37RT-2]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=528772 K8B88_RS08060 WP_000042533.1 1685386..1687407(+) (uvrB) [Escherichia coli O16:H6 strain CU37RT-2]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCGGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAATTC
TTTCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAGGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATATGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGTGTTCGTGGCGAGGTGATTGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCACGCGAGCGCATCGTCCAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGTAAAGTGCTATTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTAGGCTACTGTTCGGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACTTACCTGCCGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGTGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTCGACCCGATTATCGAAGTGCGGCC
AGTGGCAACACAGGTGGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTCACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTACAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGTTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q324B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557