Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   K7X33_RS15070 Genome accession   NZ_CP082355
Coordinates   3136805..3138826 (-) Length   673 a.a.
NCBI ID   WP_000042533.1    Uniprot ID   Q324B3
Organism   Escherichia coli strain VCSW5     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3131805..3143826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K7X33_RS15035 (K7X33_15035) ybhL 3131809..3132513 (-) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -
  K7X33_RS15040 (K7X33_15040) moaE 3132650..3133102 (-) 453 WP_000852291.1 molybdopterin synthase catalytic subunit MoaE -
  K7X33_RS15045 (K7X33_15045) moaD 3133104..3133349 (-) 246 WP_000598612.1 molybdopterin synthase sulfur carrier subunit -
  K7X33_RS15050 (K7X33_15050) moaC 3133342..3133827 (-) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  K7X33_RS15055 (K7X33_15055) moaB 3133830..3134342 (-) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  K7X33_RS15060 (K7X33_15060) moaA 3134364..3135353 (-) 990 WP_001308508.1 GTP 3',8-cyclase MoaA -
  K7X33_RS15065 (K7X33_15065) yvcK 3135750..3136658 (+) 909 WP_001308507.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  K7X33_RS15070 (K7X33_15070) uvrB 3136805..3138826 (-) 2022 WP_000042533.1 excinuclease ABC subunit UvrB Machinery gene
  K7X33_RS15075 (K7X33_15075) bioD 3139405..3140082 (-) 678 WP_000044836.1 dethiobiotin synthase -
  K7X33_RS15080 (K7X33_15080) bioC 3140075..3140830 (-) 756 WP_000246795.1 malonyl-ACP O-methyltransferase BioC -
  K7X33_RS15085 (K7X33_15085) bioF 3140817..3141971 (-) 1155 WP_000118866.1 8-amino-7-oxononanoate synthase -
  K7X33_RS15090 (K7X33_15090) bioB 3141968..3143008 (-) 1041 WP_000951213.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76226.06 Da        Isoelectric Point: 4.8843

>NTDB_id=528371 K7X33_RS15070 WP_000042533.1 3136805..3138826(-) (uvrB) [Escherichia coli strain VCSW5]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=528371 K7X33_RS15070 WP_000042533.1 3136805..3138826(-) (uvrB) [Escherichia coli strain VCSW5]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGATCTTCAGCGCCCTACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGTTGTATGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTTAACGAACATATTGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGCATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAGGC
ATTCCAGCGTGGTACTTTCCGCGTTCGTGGTGAGGTGATTGATATCTTCCCAGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTCACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCGCGCGAGCGCATCGTACAGGCGATGGAAGAGATCAAAGAAGAACT
GGCCGCCAGACGCAAAGTGCTGTTGGAGAACAACAAGTTGCTTGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCCGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGCTGGTGGTCGATGAATCACACGTCACCATTCCGCAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACGCTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACCGGATTGCTTGACCCGATAATTGAAGTGCGGCC
GGTGGCGACACAGGTTGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGAATGGCGGAAGATCTCACGGAATATCTCGAAGAACACGGCGAGCGCGTGCGTTATCTTCACTCCGATATC
GACACCGTCGAGCGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTGCTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTGTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACTATTGGTCGTGCGGCGCGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCGTCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGTCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGTATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCTAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAGATCCATGAACTCGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCACAAATTCGTGACCAGTTGCATCAGCTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q324B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557