Detailed information NTG0528141

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6J09_RS03370
• Genome accession: NZ_CP068216
• Coordinates: 702562..703605 (-)
• Length: 347 a.a.
• NCBI ID: WP_017637854.1
• Uniprot ID: A0A654BBJ5
• Organism: Staphylococcus pasteuri strain FDAARGOS_1152
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 697562..708605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J09_RS03340 (I6J09_03335)	-	697972..699213 (-)	1242	WP_208969981.1	aminopeptidase	-
I6J09_RS03345 (I6J09_03340)	-	699227..699409 (-)	183	WP_037555624.1	DUF1128 domain-containing protein	-
I6J09_RS03350 (I6J09_03345)	-	699571..700035 (+)	465	WP_017637850.1	low molecular weight protein-tyrosine-phosphatase	-
I6J09_RS03355 (I6J09_03350)	-	700040..700324 (+)	285	WP_017637851.1	hypothetical protein	-
I6J09_RS03360 (I6J09_03355)	-	700614..701852 (+)	1239	WP_017637852.1	YihY/virulence factor BrkB family protein	-
I6J09_RS03365 (I6J09_03360)	vraR	701943..702572 (-)	630	WP_017637853.1	two-component system response regulator VraR	Regulator
I6J09_RS03370 (I6J09_03365)	vraS	702562..703605 (-)	1044	WP_017637854.1	sensor histidine kinase	Regulator
I6J09_RS03375 (I6J09_03370)	liaF	703602..704303 (-)	702	WP_017637855.1	cell wall-active antibiotics response protein LiaF	-
I6J09_RS03380 (I6J09_03375)	-	704318..704704 (-)	387	WP_119622838.1	DUF2543 family protein	-
I6J09_RS03385 (I6J09_03380)	map	704855..705610 (-)	756	WP_208969982.1	type I methionyl aminopeptidase	-
I6J09_RS03390 (I6J09_03385)	-	705776..706762 (+)	987	WP_208969983.1	FUSC family protein	-
I6J09_RS03395 (I6J09_03390)	-	707147..707872 (-)	726	WP_046467432.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40047.46 Da
• Isoelectric Point: 6.2449

>NTDB_id=528141 I6J09_RS03370 WP_017637854.1 702562..703605(-) (vraS) [Staphylococcus pasteuri strain FDAARGOS_1152]
MNHYIRAIGSMLILTYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWINS
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=528141 I6J09_RS03370 WP_017637854.1 702562..703605(-) (vraS) [Staphylococcus pasteuri strain FDAARGOS_1152]
ATGAATCACTATATAAGAGCAATAGGCTCTATGCTCATTTTAACGTATAGTATGTTAACCGCATTTTTATTTATTGATAA
AGTATTTGTTAACATCATCTATTTTCAAGGTATGTTCTATACACAGATTTTTGGCATACCTGTATTCTTATTTTTAAATA
TCATAGTGATATTATTATGTATCATTGTAGGCTCTGTTTTAGCTTATAAAATTAATCAACAGAATGACTGGATTAATTCT
CAAATAGAACGATCTATTGAAGGTGAAACAGTTGGTATCAATGACCAAAATATAGAATTATATAGTGAAACACTGGAAAT
ATATCATACACTTGTACCATTAAATCAGGAATTACATCGATTAAGAATGAAAACACAAAACTTAACTAATGAAAACTACA
ACATGAACGATGTAAAAGTTAAAAAGATTATTGAAGACGAAAGACAACGTCTAGCTAGAGAATTACATGACTCAGTAAGT
CAACAATTATTCGCTGCGAGTATGATGTTATCAGCGATTAAAGAAACTAAATTAGAACCCCCATTAGACCAACAAATTCC
AGTTTTAGAGAAAATGGTACAAGATTCACAACTTGAAATGAGAGCTTTATTATTACATTTACGACCTCTAGGGTTGAAAG
ATAAGTCCTTAGGTGAAGGAATTAAAGATTTAGTTATAGATCTTCAAAAGAAAGTTCCGATGAAAGTTGTACATGAAATA
CAAGAATTTAAAGTTCCTAAAGGTATCGAAGATCATTTATTTAGAATTACTCAAGAAGCTATTTCAAATACATTAAGACA
TTCTAATGGCACTAGAGTGACGGTTGAACTATTTAATAAGCAAGATTATTTATTATTACGTATACAAGATAATGGTAAAG
GCTTTAATGTAGATGAAAAATTGGAACAAAGCTATGGTTTAAAAAATATGAGAGAACGTGCATTAGAAATTGGTGCTACA
TTCCATATCGTTTCGTTACCTGATTCCGGAACACGTATAGAAGTTAAAGCCCCATTGAACAAGGAGGATTCTTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A654BBJ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945