Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   K7H19_RS00645 Genome accession   NZ_CP082323
Coordinates   123035..124039 (+) Length   334 a.a.
NCBI ID   WP_011227724.1    Uniprot ID   Q5SM22
Organism   Thermus thermophilus strain N-1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 118035..129039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K7H19_RS00615 (K7H19_00615) - 118186..119406 (+) 1221 WP_011227721.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase -
  K7H19_RS00620 (K7H19_00620) - 119416..119964 (+) 549 WP_011227722.1 Uma2 family endonuclease -
  K7H19_RS00625 (K7H19_00625) - 119942..120916 (-) 975 WP_011227723.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
  K7H19_RS00635 (K7H19_00635) - 121113..122000 (-) 888 WP_011174227.1 acyltransferase -
  K7H19_RS00640 (K7H19_00640) era 122045..122950 (-) 906 WP_008630929.1 GTPase Era -
  K7H19_RS00645 (K7H19_00645) dprA 123035..124039 (+) 1005 WP_011227724.1 DNA-processing protein DprA Machinery gene
  K7H19_RS00650 (K7H19_00650) - 124043..124951 (-) 909 WP_011227725.1 manganese catalase family protein -
  K7H19_RS00655 (K7H19_00655) - 125061..126014 (+) 954 WP_011227726.1 hydrogen peroxide-inducible genes activator -
  K7H19_RS00660 (K7H19_00660) - 126001..126957 (+) 957 WP_164926019.1 branched-chain amino acid transaminase -
  K7H19_RS00665 (K7H19_00665) - 126947..127135 (+) 189 WP_011174222.1 hypothetical protein -
  K7H19_RS00670 (K7H19_00670) - 127137..127376 (+) 240 WP_008630920.1 hypothetical protein -
  K7H19_RS00675 (K7H19_00675) trmH 127366..127950 (-) 585 WP_011174221.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH -
  K7H19_RS00680 (K7H19_00680) hisG 127947..128567 (-) 621 WP_011174220.1 ATP phosphoribosyltransferase -

Sequence

Protein


Download         Length: 334 a.a.        Molecular weight: 36145.98 Da        Isoelectric Point: 6.5207

>NTDB_id=528113 K7H19_RS00645 WP_011227724.1 123035..124039(+) (dprA) [Thermus thermophilus strain N-1]
MDPLALALLPGIGPKRLLEVLKAEDPLGFLRERFPEAWRHLPEAEAQAERERGRAEALGVRLLGLWEEGFPEGLRALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARRLARELAEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLCRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPTDER
SLGANRLIQDGAYPVLSAEDVLSYLGMSARPKPLPGLSPEEEALYALLQEKKEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide


Download         Length: 1005 bp        

>NTDB_id=528113 K7H19_RS00645 WP_011227724.1 123035..124039(+) (dprA) [Thermus thermophilus strain N-1]
GTGGACCCCTTGGCCCTCGCCCTCCTCCCGGGCATCGGCCCCAAGCGGCTTTTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCGGCACCTCCCCGAGGCCGAGGCCCAGGCGGAAAGGGAAAGGGGGC
GCGCCGAGGCCCTAGGGGTGCGCCTCCTGGGCCTCTGGGAGGAGGGCTTCCCCGAGGGGCTGAGGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCCCC
TTGGGCCCTGGCCTTTGCCAGGAGGCTCGCCCGGGAGCTGGCCGAGGCCGGGCTTTGGGTGGTCTCGGGCCTCGCCCGGG
GCATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCTTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGGACCGGCCCTAAGCC
CGAGTTCTTTCCCCGGCGAAACCGCCTCATCGCCGGGCTTTGCCGGGCAGTGGTCGTGGTGGAGGCCCCCCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCCTGGAGCTCGGCAAGGAGGTGCTGGCCGTGCCCGGAAGGCCCACGGACGAGCGC
TCCCTGGGGGCGAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGACGTCCTCTCCTACCTGGGAAT
GTCCGCAAGGCCCAAGCCCCTCCCGGGCCTCTCCCCGGAGGAGGAAGCCCTTTACGCCCTCCTGCAGGAAAAGAAGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTCCTCACCCTCTTGGAGCTAAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(269-329)

DNA recombination-mediator protein A (DNA_processg_A)

(56-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5SM22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Thermus thermophilus HB27

98.503

100

0.985
  dprA Vibrio campbellii strain DS40M4

38.268

100

0.41
  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

45.89

87.425

0.401
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

37.255

100

0.398
  dprA Vibrio cholerae strain A1552

37.255

100

0.398