Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   I6J13_RS07030 Genome accession   NZ_CP068213
Coordinates   1438533..1439855 (-) Length   440 a.a.
NCBI ID   WP_218028116.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1156     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1433533..1444855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J13_RS07010 (I6J13_07010) - 1434885..1437464 (+) 2580 WP_006270322.1 YfhO family protein -
  I6J13_RS07025 (I6J13_07025) comE 1437784..1438533 (-) 750 WP_003071650.1 competence system response regulator transcription factor ComE Regulator
  I6J13_RS07030 (I6J13_07030) comD/comD2 1438533..1439855 (-) 1323 WP_218028116.1 sensor histidine kinase Regulator
  I6J13_RS07035 (I6J13_07035) - 1439875..1440021 (-) 147 WP_006270349.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I6J13_RS07045 (I6J13_07045) rlmH 1440304..1440783 (-) 480 WP_006270335.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6J13_RS07050 (I6J13_07050) htrA 1440988..1442178 (+) 1191 WP_006270334.1 S1C family serine protease Regulator
  I6J13_RS07055 (I6J13_07055) spo0J 1442233..1443000 (+) 768 WP_003071657.1 ParB/RepB/Spo0J family partition protein Regulator
  I6J13_RS07060 (I6J13_07060) dnaA 1443229..1444572 (+) 1344 WP_006270358.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51869.72 Da        Isoelectric Point: 9.0710

>NTDB_id=528060 I6J13_RS07030 WP_218028116.1 1438533..1439855(-) (comD/comD2) [Streptococcus constellatus strain FDAARGOS_1156]
MKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFVKVKKVK
KHSSLFLALFLSLAVSGSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKVDFKDKIVQL
NFYLLFIHFLLNVSHWLSNMKSLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLYN
EIRGFRHDYGGMLASFQSAIHTGNIREVERIYQEVLVNANLQLRSDKYTYFDLNNIGDSALRSVMIQTLFKARDYNIELT
FEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRQLDLEMIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTNIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=528060 I6J13_RS07030 WP_218028116.1 1438533..1439855(-) (comD/comD2) [Streptococcus constellatus strain FDAARGOS_1156]
GTGAAAATAGAATTTATACATTGGATTATATTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGTTATAAGAAGATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAATAC
ATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATACTTTGTTAAAGTAAAAAAAGTTAAA
AAACATTCGTCTTTATTTTTAGCACTATTTTTATCTTTAGCTGTATCAGGTTCTGAAACCTTCTTTTCAGTTATTATTTC
TTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTTTCA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGTTGATTTCAAAGATAAGATTGTACAGTTA
AATTTTTATCTATTATTCATTCATTTTTTATTAAATGTATCGCATTGGCTTAGCAATATGAAAAGTTTAAATAGTTTTTC
TAGTATGATTGCGACGATTTGCTTTTTGATGTTTATGTCAATTTTATTCTACTTACAATCTATTCGTGAAAAATATGAAA
AAGAGGAGCAAATTAAACAAAAAGAACGAGAACAGCTACAACTACAAAAGTATACAGATGAAATTGTGAGTCTTTACAAT
GAAATTCGAGGTTTTCGTCACGATTATGGTGGGATGTTGGCAAGTTTCCAATCTGCCATTCATACAGGTAATATAAGAGA
AGTAGAACGAATTTATCAAGAAGTACTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACTTATTTTGATTTAA
ATAACATTGGGGATTCAGCGCTTAGAAGCGTTATGATACAAACCTTGTTTAAGGCACGTGATTATAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTCAAGCCTTTACCGATTAAATTATTAGATCTAGTTAGAATGACAAGTGTTCTTTTAAATAA
TGCCATAGAAGGAGCAGCAGAAAGTTATCAAAAAACAATGAATGTTTCTTTGGTAGATTTGGATACAGAAACTATCTTAG
TCATTCAAAATTCACGTAAAAAAAGACAACTAGACTTAGAAATGATTTATCAAACCGATTTTTCAACAAAGGGCGAGGGA
CGAGGTTTAGGTTTAAGCAATATCAAAGAAATTATTAATAACTATGAAGGAATTATTCTTGATACAAACATTGAGGATGA
ATATTTTACACAAGTAATGAGAGTAAGGAAAGAAGGTCTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

53.846

100

0.541
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.11

99.545

0.539
  comD Streptococcus mitis SK321

47.704

89.091

0.425
  comD/comD2 Streptococcus pneumoniae TIGR4

48.67

85.455

0.416
  comD Streptococcus mitis NCTC 12261

48.138

85.455

0.411
  comD/comD1 Streptococcus pneumoniae Rx1

48.138

85.455

0.411
  comD/comD1 Streptococcus pneumoniae D39

48.138

85.455

0.411
  comD/comD1 Streptococcus pneumoniae R6

48.138

85.455

0.411