Detailed information NTG0527951

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: K7I17_RS19995
• Genome accession: NZ_CP082279
• Coordinates: 3887512..3888708 (-)
• Length: 398 a.a.
• NCBI ID: WP_013354214.1
• Uniprot ID: A0A9P1NK46
• Organism: Bacillus amyloliquefaciens strain Bam1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3882512..3893708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K7I17_RS19975 (K7I17_19975)	-	3883474..3883737 (-)	264	WP_013354210.1	hypothetical protein	-
K7I17_RS19980 (K7I17_19980)	-	3883916..3885334 (-)	1419	WP_014471292.1	cell wall metabolism sensor histidine kinase WalK	-
K7I17_RS19985 (K7I17_19985)	-	3885331..3886014 (-)	684	WP_013354212.1	response regulator transcription factor	-
K7I17_RS19990 (K7I17_19990)	-	3886228..3887139 (+)	912	WP_013354213.1	PepSY domain-containing protein	-
K7I17_RS19995 (K7I17_19995)	htrA	3887512..3888708 (-)	1197	WP_013354214.1	S1C family serine protease	Regulator
K7I17_RS20000 (K7I17_20000)	vicX	3888795..3889589 (-)	795	WP_013354215.1	MBL fold metallo-hydrolase	Regulator
K7I17_RS20005 (K7I17_20005)	-	3889605..3890444 (-)	840	WP_014471293.1	two-component system regulatory protein YycI	-
K7I17_RS20010 (K7I17_20010)	yycH	3890431..3891789 (-)	1359	WP_014471294.1	two-component system activity regulator YycH	-
K7I17_RS20015 (K7I17_20015)	walK	3891779..3893614 (-)	1836	WP_014471295.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42734.68 Da
• Isoelectric Point: 7.4579

>NTDB_id=527951 K7I17_RS19995 WP_013354214.1 3887512..3888708(-) (htrA) [Bacillus amyloliquefaciens strain Bam1]
MDYNRDDEQYAPEQPRRSKRGYFLSSLIGVIVGAALMGLLLPYWTGGDHGESSKSANQRIGSEQVKTVNVNINDAVTNMV
SRVSDSVVGVLNIQKTDIWGEGGEAGSGSGVIYKKNGNTSYIVTNHHVIEGATEIEISLKDDSRVPAELIGSDRLMDLAV
LKVKTDKIKSVAQFGNSDQVKVGEPVIAIGNPLGLEFAGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDAAINPGN
SGGALMDISGKVVGINSMKIAESAVEGIGLSIPSKLVIPVIQDLEKYGEVRRPFLGIEMKSLTDIASYHWSQTLKLPKGV
KTGAVIMGVDAFSPAGKAGLKKLDVITGFDGHKVNDIVDLRERLYRKKIGDRVKITFYRSGKKKTAEVKLTEADRLQK

Nucleotide

• Length: 1197 bp

>NTDB_id=527951 K7I17_RS19995 WP_013354214.1 3887512..3888708(-) (htrA) [Bacillus amyloliquefaciens strain Bam1]
GTGGATTATAATCGCGATGATGAACAGTACGCCCCCGAGCAGCCCCGCCGCAGCAAGAGAGGATACTTCCTTTCAAGTCT
GATCGGTGTCATCGTCGGGGCCGCGCTCATGGGTTTACTGCTGCCGTACTGGACAGGCGGAGACCATGGAGAAAGCAGCA
AAAGCGCCAATCAGCGCATCGGCAGCGAACAGGTGAAAACAGTCAACGTAAATATCAATGATGCTGTCACGAATATGGTC
AGCCGTGTATCGGATTCGGTAGTCGGCGTTCTCAATATCCAAAAGACCGATATTTGGGGAGAGGGCGGCGAAGCGGGAAG
CGGGTCCGGCGTCATTTACAAAAAGAACGGAAACACTTCTTATATCGTAACCAATCACCATGTCATTGAAGGTGCGACTG
AAATTGAGATCAGCCTGAAAGATGACTCGCGCGTGCCTGCCGAGCTGATCGGGAGCGACCGTCTGATGGATCTTGCCGTG
TTGAAGGTGAAGACTGATAAAATCAAATCGGTCGCCCAATTCGGCAATTCTGATCAAGTGAAAGTTGGCGAGCCGGTCAT
TGCGATCGGAAACCCGCTCGGACTTGAATTTGCGGGATCGGTGACACAAGGGATCATTTCAGGAACGGAAAGGGCGGTTC
CCGTTGACTCAAACGGCGACGGACAGCCTGATTGGAATGCGGAAGTGCTGCAGACCGACGCCGCGATTAATCCCGGCAAC
AGCGGCGGCGCTTTGATGGATATATCGGGCAAGGTGGTCGGCATCAACTCAATGAAGATTGCTGAATCCGCCGTTGAAGG
AATCGGCCTGTCCATCCCGTCAAAGCTTGTCATTCCCGTTATTCAGGATTTAGAAAAATACGGAGAAGTCAGACGGCCTT
TCCTCGGTATTGAGATGAAATCTTTAACGGATATTGCGAGCTACCATTGGAGCCAGACGCTCAAACTTCCGAAGGGTGTT
AAAACCGGAGCGGTCATTATGGGTGTCGACGCGTTTTCACCGGCTGGAAAAGCAGGCTTGAAAAAGCTCGACGTGATCAC
CGGATTCGACGGACATAAGGTCAATGACATTGTCGATCTCCGTGAGCGTCTGTATCGCAAAAAGATCGGCGACCGTGTCA
AGATCACGTTCTACCGTTCAGGAAAGAAAAAAACAGCGGAAGTCAAACTGACAGAAGCGGATCGATTGCAGAAATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-255)

• PDZ domain (PDZ_2) (293-390)

• Peptidase family M50 (Peptidase_M50) (320-394)

3D structure

• AlphaFold DB: A0A9P1NK46

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.687	99.497	0.435
htrA	Streptococcus gordonii str. Challis substr. CH1	41.602	97.236	0.405
htrA	Streptococcus mitis NCTC 12261	40.26	96.734	0.389