Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   K6973_RS10685 Genome accession   NZ_CP082206
Coordinates   2166134..2168116 (-) Length   660 a.a.
NCBI ID   WP_222819390.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain DY107     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2161134..2173116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6973_RS10660 (K6973_10660) cinA 2161975..2163246 (-) 1272 WP_143928078.1 competence/damage-inducible protein A Machinery gene
  K6973_RS10665 (K6973_10665) - 2163370..2163723 (-) 354 WP_222819388.1 VOC family protein -
  K6973_RS10670 (K6973_10670) - 2163726..2164298 (-) 573 WP_138126794.1 DNA-3-methyladenine glycosylase I -
  K6973_RS10675 (K6973_10675) ruvA 2164308..2164901 (-) 594 WP_129556363.1 Holliday junction branch migration protein RuvA Machinery gene
  K6973_RS10680 (K6973_10680) - 2164903..2166123 (-) 1221 WP_222819389.1 MFS transporter -
  K6973_RS10685 (K6973_10685) hexB 2166134..2168116 (-) 1983 WP_222819390.1 DNA mismatch repair endonuclease MutL Machinery gene
  K6973_RS10690 (K6973_10690) - 2168211..2169362 (-) 1152 WP_222819391.1 site-specific integrase -
  K6973_RS10695 (K6973_10695) - 2169605..2171113 (-) 1509 WP_261987937.1 ATP-binding protein -
  K6973_RS10700 (K6973_10700) rhuM 2171361..2171465 (-) 105 Protein_2071 RhuM family protein -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74530.79 Da        Isoelectric Point: 5.2198

>NTDB_id=527504 K6973_RS10685 WP_222819390.1 2166134..2168116(-) (hexB) [Streptococcus dysgalactiae strain DY107]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQVTIDIEESGLKKIQITDNGEGMSPEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEDNHGSLLVAIGGEIETLEETSTPVGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPDVSFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSKGIYYDPQRNDFFVKESDVSEKMPESNFHDTEIDKTVKDQR
TEQFPDLGENTESSSVKRASRSQDEITDADHPGLDLKNKQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=527504 K6973_RS10685 WP_222819390.1 2166134..2168116(-) (hexB) [Streptococcus dysgalactiae strain DY107]
ATGACAAACATTATTGAATTACCAGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATCGATGCTAAGAGTAGCCAAGTCACCATTGATATTGAAGAGTCTGGTCTCAAAA
AGATACAGATTACGGACAATGGTGAAGGGATGTCGCCTGAAGACCTTCCTTTGAGTTTGCGGCGACATGCTACCAGTAAA
ATAAAAAGTCAAAGTGATCTCTTTCGAATTAGAACACTTGGTTTTAGGGGAGAAGCCTTACCATCGGTTGCTTCTATCAG
TAAAATCACAATAAAAACAGCTACTAAGGAAGATAATCACGGTTCTCTTTTAGTTGCTATCGGCGGAGAAATTGAAACGC
TCGAGGAAACGTCGACGCCTGTAGGTACCAAGATTAAGGTGGAAAACCTTTTTTATAACACGCCTGCTCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAGTTAGCCCATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCAGATGTTTCTTT
CACCCTTATTAGTGATGGCCGTCAATTAACTCAGACATCAGGGACGGGGGACCTGCGGCAGGCTATTGCAGGGATTTATG
GCTTGAATACTGCCAAAAAAATGATTGCTATTTCCAATGCCGATTTGGACTTTGAAGTGTCGGGCTATGTCAGTTTACCA
GAGTTGACACGCGCCAACCGCAATTATATGACCATTTTAATCAATGGACGCTACATTAAAAATTTCTTGCTCAATCGGGC
TATTTTAGACGGTTACGGCTCTAAGTTGATGGTTGGACGTTTCCCAATTGTTGTGATTGATATTCAGATTGACCCCTATT
TGGCCGATGTCAATGTTCACCCTACTAAGCAAGAGGTCCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATTAGTACG
GCAATTTCTGAAAGTCTTAAGGAGCAAGATTTGATTCCAGATGCTCTGGAGAACTTAGCTAAATCAAGCACACGACACTT
TTCTAAACCAGAGCAAACACAACTTCCATTACAATCTAAAGGGATTTATTATGATCCTCAAAGAAATGACTTTTTTGTTA
AAGAATCGGATGTTTCTGAAAAAATGCCTGAGAGTAATTTTCATGATACAGAGATTGACAAGACTGTAAAGGATCAAAGG
ACGGAACAGTTTCCTGATTTAGGAGAAAATACAGAATCTTCCTCAGTAAAACGTGCTAGTCGATCACAGGATGAGATAAC
TGATGCTGATCACCCTGGACTTGATTTGAAAAACAAACAGAAATTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
AATCAGTGTTTCCCGAATTAGATTATTTTGGTCAGATGCACGGAACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAGGTTGACAGTAGTTT
ACAGCAGCTGTTGGTGCCCTATTTGTTTGAGTTTTCCGGCTCGGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCCTAGAAGTTTATGGGCACAATACTTTCATTCTGAGGGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTATCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTAGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTGTTGATTAATTTCAGTAAAGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(462-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

67.976

100

0.682