Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   K6976_RS02340 Genome accession   NZ_CP082202
Coordinates   468802..469443 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain SS389     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 463802..474443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS02320 (K6976_02320) - 464102..464839 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  K6976_RS02325 (K6976_02325) pknB 464839..466368 (+) 1530 Protein_420 Stk1 family PASTA domain-containing Ser/Thr kinase -
  K6976_RS11120 - 466369..466833 (+) 465 Protein_421 PASTA domain-containing protein -
  K6976_RS02330 (K6976_02330) liaF 467158..467817 (+) 660 WP_261987988.1 cell wall-active antibiotics response protein LiaF -
  K6976_RS02335 (K6976_02335) - 467814..468830 (+) 1017 WP_105256052.1 sensor histidine kinase -
  K6976_RS02340 (K6976_02340) vraR 468802..469443 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  K6976_RS02345 (K6976_02345) - 469493..470893 (+) 1401 WP_044692311.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  K6976_RS02350 (K6976_02350) - 470895..471266 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  K6976_RS02355 (K6976_02355) cysK 471292..472218 (-) 927 WP_002937015.1 cysteine synthase A -
  K6976_RS02360 (K6976_02360) - 472308..472940 (-) 633 WP_015646510.1 YigZ family protein -
  K6976_RS02365 (K6976_02365) comFA/cflA 472997..474289 (+) 1293 WP_222759851.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=527030 K6976_RS02340 WP_002937025.1 468802..469443(+) (vraR) [Streptococcus suis strain SS389]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=527030 K6976_RS02340 WP_002937025.1 468802..469443(+) (vraR) [Streptococcus suis strain SS389]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413