Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   I6J14_RS07495 Genome accession   NZ_CP068057
Coordinates   1502764..1503717 (-) Length   317 a.a.
NCBI ID   WP_115246884.1    Uniprot ID   A0A380JYU6
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1497764..1508717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS07470 (I6J14_07470) proC 1498862..1499638 (+) 777 WP_003049280.1 pyrroline-5-carboxylate reductase -
  I6J14_RS10950 - 1499777..1500214 (-) 438 WP_003049278.1 hypothetical protein -
  I6J14_RS07480 (I6J14_07480) - 1500232..1500837 (-) 606 WP_236593264.1 CPBP family intramembrane glutamic endopeptidase -
  I6J14_RS07485 (I6J14_07485) - 1500993..1501199 (-) 207 WP_003049274.1 helix-turn-helix transcriptional regulator -
  I6J14_RS07490 (I6J14_07490) - 1501509..1502705 (-) 1197 WP_003049273.1 acetate kinase -
  I6J14_RS07495 (I6J14_07495) comYH 1502764..1503717 (-) 954 WP_115246884.1 class I SAM-dependent methyltransferase Machinery gene
  I6J14_RS07500 (I6J14_07500) comGG 1503780..1504103 (-) 324 WP_236593265.1 competence type IV pilus minor pilin ComGG -
  I6J14_RS07505 (I6J14_07505) comGF 1504132..1504572 (-) 441 WP_003049266.1 competence type IV pilus minor pilin ComGF -
  I6J14_RS07510 (I6J14_07510) comGE 1504553..1504849 (-) 297 WP_003061797.1 competence type IV pilus minor pilin ComGE -
  I6J14_RS07515 (I6J14_07515) comGD 1504806..1505234 (-) 429 WP_115252504.1 competence type IV pilus minor pilin ComGD -
  I6J14_RS07520 (I6J14_07520) comYC 1505209..1505535 (-) 327 WP_115246891.1 competence type IV pilus major pilin ComGC Machinery gene
  I6J14_RS07525 (I6J14_07525) comYB 1505537..1506568 (-) 1032 WP_003049254.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6J14_RS07530 (I6J14_07530) comYA 1506504..1507445 (-) 942 WP_003049251.1 competence type IV pilus ATPase ComGA Machinery gene
  I6J14_RS07535 (I6J14_07535) - 1507525..1507890 (-) 366 WP_003049248.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36018.92 Da        Isoelectric Point: 4.7910

>NTDB_id=526739 I6J14_RS07495 WP_115246884.1 1502764..1503717(-) (comYH) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MNFEKIEEAYQLLLENSQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNINKLKALHLTKEEWRRAYQFIFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKKLDYVGIELDDLLIDLSASIAEVMDSS
ARFIQEDAVRPQLLKESDVVISDLPVGYYPNDDIAKRYKVASSEEHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSSQ
SQLLKNWLTGYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPTETFVYPIRDLKLAENIHDFMQNFKKWKQDNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=526739 I6J14_RS07495 WP_115246884.1 1502764..1503717(-) (comYH) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGAATTTTGAAAAAATTGAAGAAGCCTATCAGTTACTTTTAGAGAATAGTCAACTGATTGAAAACGATCTAAAAACACA
TATTTATGATGCCATCGTTGAGCAAAACTCTTTTTATTTAGGTGCTGAGGGAGCTAGTCCTCAAGTTGCCCAGAACATTA
ACAAACTGAAAGCCTTACACCTGACTAAAGAAGAATGGCGTAGAGCTTACCAGTTTATTTTTATTAAGGCAGCTCAGACT
GAGCAGCTCCAAGCAAACCATCAGTTCACGCCAGATGCTATTGGTTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
CAAAGATAGCCTAGAAGTCCTTGAAATTGGCAGTGGTACGGGAAATCTAGCACAAACTCTCCTCAATAATACGAGTAAGA
AACTTGATTATGTAGGGATTGAACTTGATGACCTCTTAATTGATTTATCAGCAAGTATTGCTGAAGTAATGGACTCTTCA
GCTCGTTTTATTCAAGAAGATGCGGTAAGACCGCAATTGTTAAAAGAAAGCGACGTTGTTATCAGTGACTTGCCAGTGGG
TTATTATCCTAATGATGACATTGCTAAGCGCTATAAGGTAGCTAGTTCTGAGGAACACACCTATGCTCATCATTTACTCA
TGGAACAATCTTTAAAGTATTTGAAAAAAGATGGTTTTGCCATTTTCTTGGCACCTGTCAATTTGTTAACAAGCTCTCAG
AGCCAATTGTTGAAAAATTGGTTAACTGGCTATGCCCAGGTAGTGGCCTTGATTACTCTACCAGATTCTATATTTGGTCA
TCCCTCAAATGCTAAGTCCATTATTGTCTTGCAAAAGCAGACAGACCATCCGACGGAAACCTTTGTTTATCCTATTCGAG
ACTTGAAACTTGCAGAGAATATTCATGACTTTATGCAAAATTTCAAAAAATGGAAACAGGATAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-290)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380JYU6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

66.456

99.685

0.662
  comYH Streptococcus mutans UA159

66.139

99.685

0.659