Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DMB76_RS04440 Genome accession   NZ_CP068029
Coordinates   931848..932477 (+) Length   209 a.a.
NCBI ID   WP_115313032.1    Uniprot ID   A0A380H495
Organism   Staphylococcus saccharolyticus strain 13T0028     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 926848..937477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DMB76_RS04410 (DMB76_004410) isaB 927039..927590 (+) 552 WP_115313026.1 immunodominant staphylococcal antigen IsaB family protein -
  DMB76_RS04415 (DMB76_004415) - 927667..928656 (-) 990 WP_115313027.1 FUSC family protein -
  DMB76_RS04420 (DMB76_004420) map 928833..929588 (+) 756 WP_115313028.1 type I methionyl aminopeptidase -
  DMB76_RS04425 (DMB76_004425) - 929719..930099 (+) 381 WP_115313029.1 hypothetical protein -
  DMB76_RS04430 (DMB76_004430) liaF 930114..930815 (+) 702 WP_115313030.1 cell wall-active antibiotics response protein LiaF -
  DMB76_RS04435 (DMB76_004435) vraS 930812..931846 (+) 1035 WP_115313031.1 sensor histidine kinase Regulator
  DMB76_RS04440 (DMB76_004440) vraR 931848..932477 (+) 630 WP_115313032.1 two-component system response regulator VraR Regulator
  DMB76_RS04445 (DMB76_004445) - 932535..933791 (-) 1257 WP_115313033.1 YihY/virulence factor BrkB family protein -
  DMB76_RS04450 (DMB76_004450) - 934148..934432 (-) 285 WP_115313034.1 YtxH domain-containing protein -
  DMB76_RS04455 (DMB76_004455) - 934439..934903 (-) 465 WP_115313035.1 low molecular weight protein-tyrosine-phosphatase -
  DMB76_RS04460 (DMB76_004460) - 935044..935250 (+) 207 WP_115313036.1 DUF1128 domain-containing protein -
  DMB76_RS04465 (DMB76_004465) - 935262..936503 (+) 1242 WP_115313037.1 aminopeptidase -
  DMB76_RS04470 (DMB76_004470) - 936589..937119 (+) 531 WP_115314122.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23554.22 Da        Isoelectric Point: 5.1732

>NTDB_id=526370 DMB76_RS04440 WP_115313032.1 931848..932477(+) (vraR) [Staphylococcus saccharolyticus strain 13T0028]
MEIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAIEKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIANAVRKTSQGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGHSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=526370 DMB76_RS04440 WP_115313032.1 931848..932477(+) (vraR) [Staphylococcus saccharolyticus strain 13T0028]
GTGGAGATTAAAGTTTTATTTGTAGATGATCATGAAATGGTCAGAATTGGTATTTCTAGTTATCTTTCAACTCAACCAGA
TATTGAGGTTGTAGGAGAGGGGGCTTCAGGTAAAGAAGCAATTGAGAAAGCTCATGAGTTGAAACCAGATTTAATTTTAA
TGGATTTACTTATGGAAGATATGGATGGTGTAGAGGCAACTACGCAAATTAAAAAGGATTTACCGCATATTAAAGTGGTT
ATGCTAACAAGTTTTATTGAAGATAAAGAAGTATACCGCGCCCTTGATGCAGGTGTAGATAGCTACATTCTTAAAACAAC
AAGTGCAAGTGATATTGCTAATGCTGTTCGTAAAACTTCGCAAGGAGAATCAGTTTTTGAACCTGAAGTTTTAGTGAAAA
TGCGTAATCGTATGAAAAAACGTGCAGAATTATATGAAATGCTTACAGAACGTGAAATGGAAATATTGCTACTCATTGCA
AAAGGACACTCTAATCAAGAAATAGCAAGTGCATCACACATCACAATTAAAACCGTAAAAACACACGTAAGTAATATTTT
AAGTAAATTAGAGGTCCAAGATAGAACACAAGCAGTGATTTATGCTTTTCAACATAATCTTATTCAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.694

100

0.957
  degU Bacillus subtilis subsp. subtilis str. 168

35.111

100

0.378