Detailed information NTG0526133

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: JJN14_RS01135
• Genome accession: NZ_CP067992
• Coordinates: 240320..241330 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090627.1
• Uniprot ID: I0SX71
• Organism: Streptococcus mitis strain S022-V7-A3
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 235320..246330

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JJN14_RS01105 (JJN14_01105)	folP	235783..236763 (+)	981	WP_201058687.1	dihydropteroate synthase	-
JJN14_RS01110 (JJN14_01110)	-	236765..238087 (+)	1323	WP_201058688.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
JJN14_RS01115 (JJN14_01115)	folE	238068..238622 (+)	555	WP_201058689.1	GTP cyclohydrolase I FolE	-
JJN14_RS01120 (JJN14_01120)	folK	238664..239476 (+)	813	WP_201058690.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
JJN14_RS10015	-	239485..239757 (-)	273	WP_236253699.1	hypothetical protein	-
JJN14_RS01130 (JJN14_01130)	-	239764..240081 (-)	318	WP_000886037.1	DUF960 domain-containing protein	-
JJN14_RS01135 (JJN14_01135)	ccpA	240320..241330 (+)	1011	WP_001090627.1	catabolite control protein A	Regulator
JJN14_RS01140 (JJN14_01140)	-	241381..242343 (-)	963	WP_201058691.1	asparaginase	-
JJN14_RS01145 (JJN14_01145)	-	242409..243797 (+)	1389	WP_201058692.1	Cof-type HAD-IIB family hydrolase	-
JJN14_RS01150 (JJN14_01150)	-	243854..244306 (-)	453	WP_004260486.1	universal stress protein	-
JJN14_RS01155 (JJN14_01155)	-	244470..244769 (+)	300	WP_120770873.1	hypothetical protein	-
JJN14_RS01160 (JJN14_01160)	-	245032..246246 (+)	1215	WP_000666455.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37169.19 Da
• Isoelectric Point: 5.3350

>NTDB_id=526133 JJN14_RS01135 WP_001090627.1 240320..241330(+) (ccpA) [Streptococcus mitis strain S022-V7-A3]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=526133 JJN14_RS01135 WP_001090627.1 240320..241330(+) (ccpA) [Streptococcus mitis strain S022-V7-A3]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACGGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAACACCCGTAAAAAAGTGCTTGAGGTGATTGATCGTTTGGATTACCGTCCAAATG
CCGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTTGTGATTCCCAATATTACCAATGGCTATTTCTCA
ACGCTTGCTAAAGGGATTGATGATATCGCTGAAATGTACAAGTACAATATTGTCCTTGCTAATAGTGATGAGGACGATGA
CAAGGAAGTTTCAGTTGTCAATACACTATTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGCTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGAACACCGGTTGTTCTTGCAGGAACTGTGGATGTAGAACATCAGCTTCCAAGT
GTCAATATTGACTACAAACAAGCAACGATTGATGCAGTGACCTACCTTGCTAAAGAAAATGAGCGCATTGCTTTTGTTAG
CGGTCCACTAGTGGATGATATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGGATTTCTT
ATAGCGAAGGATTGGTATTTGAGTCTAAATACACTTATGAAGATGGCTATGCCTTGGCAGAACGCTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTCTTGAACGGTCTTGCTGATAAGGGTGTGTCAGTACC
AGAAGAGTTTGAAATCATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: I0SX71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.536	100	0.955
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.521	99.405	0.89
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	98.512	0.571