Detailed information NTG0524342

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: JHX98_RS05080
• Genome accession: NZ_CP067010
• Coordinates: 979657..980967 (-)
• Length: 436 a.a.
• NCBI ID: WP_011888847.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain iGAS376
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 974657..985967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JHX98_RS05055 (JHX98_05055)	-	975260..976312 (-)	1053	WP_076640667.1	BMP family protein	-
JHX98_RS05060 (JHX98_05060)	-	976406..976795 (-)	390	WP_002984531.1	cytidine deaminase	-
JHX98_RS05065 (JHX98_05065)	-	977449..978042 (-)	594	WP_002989699.1	class I SAM-dependent methyltransferase	-
JHX98_RS05070 (JHX98_05070)	coaA	978310..979230 (+)	921	WP_002984525.1	type I pantothenate kinase	-
JHX98_RS05075 (JHX98_05075)	rpsT	979284..979532 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
JHX98_RS05080 (JHX98_05080)	ciaH	979657..980967 (-)	1311	WP_011888847.1	HAMP domain-containing sensor histidine kinase	Regulator
JHX98_RS05085 (JHX98_05085)	ciaR	980960..981634 (-)	675	WP_002984519.1	response regulator transcription factor	Regulator
JHX98_RS05090 (JHX98_05090)	-	981979..984516 (-)	2538	WP_011888846.1	M1 family metallopeptidase	-
JHX98_RS05095 (JHX98_05095)	phoU	984721..985374 (-)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50211.80 Da
• Isoelectric Point: 9.4081

>NTDB_id=524342 JHX98_RS05080 WP_011888847.1 979657..980967(-) (ciaH) [Streptococcus pyogenes strain iGAS376]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLRSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=524342 JHX98_RS05080 WP_011888847.1 979657..980967(-) (ciaH) [Streptococcus pyogenes strain iGAS376]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGACAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAACGCCGGTTGAGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAACGTTACGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGTGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.666	100	0.578
ciaH	Streptococcus pneumoniae Rx1	51.142	100	0.514
ciaH	Streptococcus pneumoniae D39	51.142	100	0.514
ciaH	Streptococcus pneumoniae R6	51.142	100	0.514
ciaH	Streptococcus pneumoniae TIGR4	51.142	100	0.514