Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/blpC   Type   Regulator
Locus tag   SMUGS5_RS08585 Genome accession   NC_018089
Coordinates   1776174..1776314 (+) Length   46 a.a.
NCBI ID   WP_002267610.1    Uniprot ID   Q99QI5
Organism   Streptococcus mutans GS-5     
Function   binding to ComD; induce autophosphorylation of ComD; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context


Location: 1771174..1781314
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS08560 (SMUGS5_08510) - 1771239..1771451 (-) 213 WP_002263744.1 Blp family class II bacteriocin -
  SMUGS5_RS10230 (SMUGS5_08515) - 1771856..1772020 (-) 165 WP_002265308.1 hypothetical protein -
  SMUGS5_RS10690 - 1772460..1772672 (+) 213 Protein_1664 IS3 family transposase -
  SMUGS5_RS08570 (SMUGS5_08525) - 1772795..1773199 (-) 405 WP_002274065.1 hypothetical protein -
  SMUGS5_RS08575 (SMUGS5_08530) - 1773346..1773765 (-) 420 WP_002263913.1 hypothetical protein -
  SMUGS5_RS08580 (SMUGS5_08535) - 1775146..1775547 (-) 402 WP_002310604.1 hypothetical protein -
  SMUGS5_RS10505 - 1775678..1775907 (-) 230 Protein_1668 Blp family class II bacteriocin -
  SMUGS5_RS08585 (SMUGS5_08550) comC/blpC 1776174..1776314 (+) 141 WP_002267610.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  SMUGS5_RS08590 (SMUGS5_08555) comD/blpH 1776456..1777781 (-) 1326 WP_014835041.1 sensor histidine kinase Regulator
  SMUGS5_RS08595 (SMUGS5_08560) comE/blpR 1777778..1778530 (-) 753 WP_002270252.1 response regulator transcription factor Regulator
  SMUGS5_RS08600 (SMUGS5_08565) - 1779001..1779639 (-) 639 WP_002271525.1 VTT domain-containing protein -
  SMUGS5_RS08605 (SMUGS5_08570) - 1779687..1780313 (-) 627 WP_002265453.1 hypothetical protein -

Sequence


Protein


Download         Length: 46 a.a.        Molecular weight: 5211.06 Da        Isoelectric Point: 10.4929

>NTDB_id=52052 SMUGS5_RS08585 WP_002267610.1 1776174..1776314(+) (comC/blpC) [Streptococcus mutans GS-5]
MKKTLSLKNDFKEIKTDELEIIIGGSGSLSTFFRLFNRSFTQALGK

Nucleotide


Download         Length: 141 bp        

>NTDB_id=52052 SMUGS5_RS08585 WP_002267610.1 1776174..1776314(+) (comC/blpC) [Streptococcus mutans GS-5]
ATGAAAAAAACACTATCATTAAAAAATGACTTTAAAGAAATTAAGACTGATGAATTAGAGATTATCATTGGCGGAAGCGG
AAGCCTATCAACATTTTTCCGGCTGTTTAACAGAAGTTTTACACAAGCTTTGGGAAAATAA

Domains


Predicted by InterproScan.

(1-32)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  PDB 2I2J

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/blpC Streptococcus mutans UA159

100

100

1


Multiple sequence alignment